product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Guanylate kinase
catalog :
MBS1476775
quantity :
0.01 mg (E-Coli)
price :
110 USD
more info or order :
product information
catalog number :
MBS1476775
products type :
Recombinant Protein
products full name :
Recombinant Human Guanylate kinase
products short name :
Guanylate kinase
products name syn :
GMP kinase
other names :
guanylate kinase isoform b; Guanylate kinase; guanylate kinase; guanylate kinase 1; GMP kinase
products gene name :
GUK1
other gene names :
GUK1; GUK1; GMK; GMK
uniprot entry name :
KGUA_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
2-197
sequence length :
197
sequence :
SGPRPVVLSGPSGAGKSTLLKRLLQEHSGIFGFSVSHTT
RNPRPGEENGKDYYFVTREVMQRDIAAGDFIEHAEFSGN
LYGTSKVAVQAVQAMNRICVLDVDLQGVRNIKATDLRPI
YISVQPPSLHVLEQRLRQRNTETEESLVKRLAAAQADME
SSKEPGLFDVVIINDSLDQAYAELKEALSEEIKKAQRTG
A
RNPRPGEENGKDYYFVTREVMQRDIAAGDFIEHAEFSGN
LYGTSKVAVQAVQAMNRICVLDVDLQGVRNIKATDLRPI
YISVQPPSLHVLEQRLRQRNTETEESLVKRLAAAQADME
SSKEPGLFDVVIINDSLDQAYAELKEALSEEIKKAQRTG
A
purity :
Greater than 90% as determined by SDS-PAGE.
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
other info2 :
Species: Homo sapiens (Human)
products categories :
Cancer
products description :
Essential for recycling GMP and indirectly, cGMP.
products references :
Human guanylate kinase (GUK1): cDNA sequence, expression and chromosomal localisation."
Fitzgibbon J., Katsanis N., Wells D., Delhanty J., Vallins W., Hunt D.M.
FEBS Lett. 385:185-188(1996)
ncbi gi num :
4504221
ncbi acc num :
NP_000849.1
ncbi gb acc num :
NM_000858.5
uniprot acc num :
Q16774
ncbi mol weight :
37.58kD
ncbi pathways :
Abacavir Metabolism Pathway (1270228); Abacavir Transport And Metabolism Pathway (1270226); Guanine Ribonucleotide Biosynthesis IMP = GDP,GTP Pathway (618581); Guanine Ribonucleotide Biosynthesis IMP = GDP,GTP Pathway (468243); Metabolic Pathways (132956); Metabolism Pathway (1269956); Metabolism Of Nucleotides Pathway (1270133); Purine Metabolism Pathway (82944); Purine Metabolism Pathway (307); Synthesis And Interconversion Of Nucleotide Di- And Triphosphates Pathway (1270142)
ncbi summary :
The protein encoded by this gene is an enzyme that catalyzes the transfer of a phosphate group from ATP to guanosine monophosphate (GMP) to form guanosine diphosphate (GDP). The encoded protein is thought to be a good target for cancer chemotherapy. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
uniprot summary :
GUK1: Essential for recycling GMP and indirectly, cGMP. Belongs to the guanylate kinase family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Kinase, other; Nucleotide Metabolism - purine; EC 2.7.4.8. Chromosomal Location of Human Ortholog: 1q32-q41. Cellular Component: cytosol. Molecular Function: ATP binding; guanylate kinase activity. Biological Process: ATP metabolic process; dATP metabolic process; dGDP biosynthetic process; dGMP metabolic process; drug metabolic process; GDP biosynthetic process; GDP-mannose metabolic process; GMP metabolic process; nucleobase, nucleoside and nucleotide interconversion; nucleobase, nucleoside and nucleotide metabolic process; nucleotide phosphorylation; purine nucleotide metabolic process
size1 :
0.01 mg (E-Coli)
price1 :
110 USD
size2 :
0.05 mg (E-Coli)
price2 :
190
size3 :
0.2 mg (E-Coli)
price3 :
460
size4 :
0.5 mg (E-Coli)
price4 :
750
size5 :
0.05 mg (Baculovirus)
price5 :
945
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
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