Recombinant Human Actin, Alpha 2, Smooth Muscle, Aorta | MyBioSource MBS146566 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Human Actin, Alpha 2, Smooth Muscle, Aorta

catalog :

MBS146566

quantity :

0.002 mg

price :

140 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS146566

products type :

Recombinant Protein

products full name :

Recombinant Human Actin, Alpha 2, Smooth Muscle, Aorta

products short name :

[Actin]

products name syn :

[ACTA2 Human; Actin, Alpha 2, Smooth Muscle, Aorta Human Recombinant; Actin Alpha 2 Smooth Muscle Aorta; Cell Growth-Inhibiting Gene 46 Protein; Actin Aortic Smooth Muscle; Alpha-Cardiac Actin; Alpha-Actin-2; MYMY5; ACTSA; ACTVS; AAT6]

other names :

[actin, aortic smooth muscle; Actin, aortic smooth muscle; actin, aortic smooth muscle; alpha-cardiac actin; cell growth-inhibiting gene 46 protein; actin, alpha 2, smooth muscle, aorta; Alpha-actin-2; Cell growth-inhibiting gene 46 protein]

products gene name :

[ACTA2]

other gene names :

[ACTA2; ACTA2; AAT6; ACTSA; MYMY5; ACTSA; ACTVS]

uniprot entry name :

ACTA_HUMAN

host :

E Coli

sequence length :

377

sequence :

MGSSHHHHHH SSGLVPRGSH MGSHM EEEDS TALVCDNGSG LCKAGFAGDD APRAVFPSIV GRPRHQGVMV GMGQKDSYVG DEAQSKRGIL TLKYPIEHGI ITNWDDMEKI WHHSFYNELR VAPEEHPTLL TEAPLNPKAN REKMTQIMFE TFNVPAMYVA IQAVLSLYAS GRTTGIVLDS GDGVTHNVPI YEGYALPHAI MRLDLAGRDL TDYLMKILTE RGYSFVTTAE REIVRDIKEK LCYVALDFEN EMATAASSSS LEKSYELPDG QVITIGNERF RCPETLFQPS FIGMESAGIH ETTYNSIMKC DIDIRKDLYA NNVLSGGTTM YPGIADRMQK EITALAPSTM KIKIIAPPER KYSVWIGGSI LASLSTFQQM WISKQEYDEA GPSIVHRKCF

purity :

Greater than 85% as determined by SDS-PAGE.

form :

The ACTA2 solution (1mg/mL) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl and 10% glycerol.

storage stability :

Store at 4°C if entire vial will be used within 2-4 weeks. Store frozen at -20°C for longer periods of time. For long term sotrage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

other info1 :

Physical Appearance: Sterile filtered colorless solution

products categories :

RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; Actin

products description :

ACTA2 Human Recombinant produced in E. coli is a single polypeptide chain containing 400 amino acids (3-377) and having a molecular mass of 44.4 kDa. ACTA2 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

ncbi gi num :

213688375

ncbi acc num :

NP_001135417.1

ncbi gb acc num :

NM_001141945.1

uniprot acc num :

P62736

ncbi pathways :

Muscle Contraction Pathway (106261); Myometrial Relaxation And Contraction Pathways (198759); Smooth Muscle Contraction Pathway (161025); Striated Muscle Contraction Pathway (198903); Vascular Smooth Muscle Contraction Pathway (96530); Vascular Smooth Muscle Contraction Pathway (96866)

ncbi summary :

The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2008]

uniprot summary :

ACTA2: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Up-regulated in response to enterovirus 71 (EV71) infection. Belongs to the actin family. Protein type: Cytoskeletal; Contractile; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 10q23.3. Cellular Component: extracellular space; smooth muscle contractile fiber; protein complex; cytoplasm; cytosol; actin cytoskeleton. Molecular Function: protein kinase binding; ATP binding. Biological Process: muscle contraction; response to virus; regulation of blood pressure; vascular smooth muscle contraction. Disease: Moyamoya Disease 5; Multisystemic Smooth Muscle Dysfunction Syndrome; Aortic Aneurysm, Familial Thoracic 6

size1 :

0.002 mg

price1 :

140 USD

size2 :

0.01 mg

price2 :

205

size3 :

1 mg

price3 :

5015

more info or order :

MyBioSource product webpage