product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Fc-Epsilon RI-Alpha
catalog :
MBS146370
quantity :
0.005 mg
price :
140 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS146370
products type :
Recombinant Protein
products full name :
Recombinant Human Fc-Epsilon RI-Alpha
products short name :
[Fc-Epsilon RI-Alpha]
products name syn :
[Fc Fragment Of IgE; High Affinity I; Receptor For; Alpha Polypeptide; FCE1A; IgE Fc Receptor Subunit Alpha; FcERI; Fc-Epsilon RI-Alpha; Fc Epsilon RI Alpha-Chain; Fc IgE Receptor; Alpha Polypeptide; High Affinity Immunoglobulin Epsilon Receptor Alpha-Subunit; High Affinity Immunoglobulin Epsilon Receptor Subunit Alpha; Immunoglobulin E Receptor; High-Affinity; Of Mast Cells; Alpha Polypeptide]
other names :
[high affinity immunoglobulin epsilon receptor subunit alpha; High affinity immunoglobulin epsilon receptor subunit alpha; high affinity immunoglobulin epsilon receptor subunit alpha; Fc IgE receptor, alpha polypeptide; Fc epsilon RI alpha-chain; Fc-epsilon RI-alpha; high affinity immunoglobulin epsilon receptor alpha-subunit; igE Fc receptor subunit alpha; immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide; Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide; Fc-epsilon RI-alpha; FcERI; IgE Fc receptor subunit alpha]
products gene name :
[FCER1A]
other gene names :
[FCER1A; FCER1A; FCE1A; FcERI; FCE1A; FcERI]
uniprot entry name :
FCERA_HUMAN
host :
Escherichia Coli
sequence length :
257
sequence :
MGSSHHHHHH SSGLVPRGSH MGS VPQKPKV SLNPPWNRIF KGENVTLTCN GNNFFEVSST KWFHNGSLSE ETNSSLNIVN AKFEDSGEYK CQHQQVNESE PVYLEVFSDW LLLQASAEVV MEGQPLFLRC HGWRNWDVYK VIYYKDGEAL KYWYENHNIS ITNATVEDSG TYYCTGKVWQ LDYESEPLNI TVIKAPREKY WLQ
purity :
Greater than 85% as determined by SDS-PAGE.
form :
Sterile filtered colorless solution. FCER1A protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 30% glycerol and 1mM DTT.
storage stability :
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze thaw cycles.
other info1 :
Physical Appearance: Sterile Filtered colorless solution.
products categories :
RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins
products description :
Description: FCER1A Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 203 amino acids (26-205aa) and having a molecular mass of 23.4kDa. FCER1A is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
ncbi gi num :
4503675
ncbi acc num :
NP_001992.1
ncbi gb acc num :
NM_002001.3
uniprot acc num :
P12319
ncbi pathways :
Asthma Pathway (83120); Asthma Pathway (532); Fc Epsilon RI Signaling Pathway (83082); Fc Epsilon RI Signaling Pathway (493); Fc Epsilon Receptor (FCERI) Signaling Pathway (833825); Fc-epsilon Receptor I Signaling In Mast Cells Pathway (138050); Immune System Pathway (106386); Innate Immune System Pathway (106387)
ncbi summary :
The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit. [provided by RefSeq, Aug 2011]
uniprot summary :
Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
size1 :
0.005 mg
price1 :
140 USD
size2 :
0.02 mg
price2 :
205
size3 :
1 mg
price3 :
2665
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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