protein

Recombinant Human Ribonuclease 7

MBS146191

0.002 mg

140 USD

Recombinant Protein

Recombinant Human Ribonuclease 7

[Ribonuclease 7]

[Ribonuclease, RNase A Family, 7, Skin-Derived Antimicrobial Protein 2, RNase 7, SAP-2, EC 3.1.27.5, EC 3.1.27., EC 3.1.27, Ribonuclease 7]

[ribonuclease 7; Ribonuclease 7; ribonuclease 7; RNase 7; SAP-2; skin-derived antimicrobial protein 2; ribonuclease, RNase A family, 7; Skin-derived antimicrobial protein 2; SAP-2]

[RNASE7]

[RNASE7; RNASE7; RNase 7; SAP-2]

RNAS7_HUMAN

Escherichia Coli

156

MGSSHHHHHHSSGLVPRGSH MGS KPKGMTS SQWFKIQHMQ PSPQACNSAM KNINKHTKRC KDLNTFLHEPFSSVAATCQT PKIACKNGDK NCHQSHGPVS LTMCKLTSGK YPNCRYKEKR QNKSYVVACK PPQKKDSQQFHLVPVHLDRV L

Greater than 90% as determined by SDS-PAGE.

RNASE7 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH8.0) and 10% glycerol 1mM DTT.solution.

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles

Physical Appearance: Sterile Filtered colorless

. Amino acid sequence: MGSSHHHHHH SSGLVPRGSH MGSKPKGMTS SQWFKIQHMQ PSPQACNSAM KNINKHTKRC KDLNTFLHEP FSSVAATCQT PKIACKNGDK NCHQSHGPVS LTMCKLTSGK YPNCRYKEKR QNKSYVVACK PPQKKDSQQF HLVPVHLDRV L.

ENZYMES

RNASE7 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 151 amino acids (29-156 a.a) and having a molecular mass of 16.9kDa. RNASE7 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

153252081

NP_115961.2

NM_032572.3

The protein encoded by this gene belongs to the pancreatic ribonuclease family, a subset of the ribonuclease A superfamily. The protein has broad-spectrum antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014]

RNASE7: Exhibits a potent RNase activity. Has broad-spectrum antimicrobial activity against many pathogenic microorganisms and remarkably potent activity (lethal dose of 90% 30 nM) against a vancomycin resistant Enterococcus faecium. Belongs to the pancreatic ribonuclease family. Protein type: Ribonuclease; Secreted; EC 3.1.27.-; RNA-binding; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 14q11.2. Cellular Component: extracellular region. Molecular Function: peptidoglycan binding; nucleic acid binding; lipopolysaccharide binding; endonuclease activity; ribonuclease activity. Biological Process: defense response to Gram-positive bacterium; response to bacterium; antibacterial humoral response; innate immune response; membrane disruption in another organism; defense response to Gram-negative bacterium

0.002 mg

140 USD

0.01 mg

205

1 mg

5015