catalog number :
MBS145939
products type :
Recombinant Protein
products full name :
Recombinant Borrelia Garinii VlsE1
products short name :
[VlsE1]
products name syn :
[Borrelia OspA; Borrelia Burgdorferi Outer Surface Protein A Recombinant; Borrelia Garinii VlsE1]
other names :
[VlsE1; VlsE1; VlsE1]
other gene names :
[vlsE]
uniprot entry name :
O06878_BORBG
purity :
Greater than 80.0% as determined by SDS-PAGE.
form :
Borrelia OspA (1.02 mg/mL) is supplied in 20 mM HEPES buffer pH 8.0, 200mM NaCI and 20% Glycerol.
storage stability :
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.
other info2 :
Physical Appearance: Sterile filtered clear solution.
products categories :
VIRAL ANTIGENS- BORRELIA PROTEIN; Viral Antigens; Borrelia
products description :
Description: Recombinant Borrelia Burgdorferi OspA produced in E Coli is a non-glycosylated, full-length polypeptide chain having a calculated molecular mass of 28,577 Dalton. Borrelia OspA is expressed with a -6x His tag at N-terminus and purified by proprietary chromatographic techniques. Introduction: Borrelia belongs to a genus of bacteria of the spirochete phylum. Borrelia causes borreliosis, which is a zoonotic, vector-borne disease transmitted mainly by ticks and some by lice, depending on the species. Of the 36 known species of Borrelia, 12 are distinguished to cause Lyme disease or borreliosis and are transmitted by ticks. The main Borrelia species causing Lyme disease are Borrelia burgdorferi, Borrelia afzelii, and Borrelia garinii. The Borrelia genus members have a linear chromosome which is about 900 kbp in length as well as an excess of both linear and circular plasmids in the 5-220 kbp size range. The plasmids are atypical, as compared to most bacterial plasmids, since they contain many paralogous sequences, a large number of pseudogenes and, in some cases, essential genes. Moreover, a number of the plasmids have features suggesting that they are prophages.
ncbi acc num :
AAC45733.1
uniprot summary :
The Vlp and Vsp proteins are antigenically distinct proteins, only one vlp or vsp gene is transcriptionally active at any one time. Switching between these genes is a mechanism of host immune response evasion.