product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Rat Nephrin (Nphs1), partial
catalog :
MBS1455114
quantity :
0.5 mg (E-Coli)
price :
715 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1455114
products type :
Recombinant Protein
products full name :
Recombinant Rat Nephrin (Nphs1), partial
products short name :
Nephrin (Nphs1), partial
products name syn :
Nephrin; Renal glomerulus-specific cell adhesion receptor
other names :
nephrin; Nephrin; nephrin; nephrosis 1 homolog, nephrin; renal glomerulus-specific cell adhesion receptor; nephrosis 1, congenital, Finnish type (nephrin); Renal glomerulus-specific cell adhesion receptor
products gene name :
Nphs1
products gene name syn :
Nphs1; Nphn
other gene names :
Nphs1; Nphs1; Nphn
uniprot entry name :
NPHN_RAT
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
purity :
>90%
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Rattus norvegicus (Rat)
products description :
Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion.
ncbi gi num :
12018318
ncbi acc num :
NP_072150.1
ncbi gb acc num :
NM_022628.1
uniprot acc num :
Q9R044
ncbi mol weight :
30kD
ncbi pathways :
Cell-Cell Communication Pathway (1010357); Nephrin Interactions Pathway (1010369)
ncbi summary :
renal protein localized specifically to glomerular capillary walls; may contribute to the development of proteinuria in renal disease [RGD, Feb 2006]
uniprot summary :
NPHS1: Seems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion. Interacts with CD2AP (via C-terminal domain). Interacts with MAGI1 (via PDZ 2 and 3 domains) forming a tripartite complex with IGSF5/JAM4. Interacts with DDN; the interaction is direct. Self-associates (via the Ig-like domains). Also interacts (via the Ig-like domains) with KIRREL/NEPH1 and KIRREL2; the interaction with KIRREL is dependent on KIRREL glycosylation. Forms a complex with ACTN4, CASK, IQGAP1, MAGI2, SPTAN1 and SPTBN1. Interacts with NPHS2. Specifically expressed in podocytes of kidney glomeruli. Belongs to the immunoglobulin superfamily. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Immunoglobulin superfamily; Cell adhesion. Cellular Component: protein complex; cell projection; membrane; integral to membrane; plasma membrane; intracellular; lipid raft. Molecular Function: protein domain specific binding; protein binding; spectrin binding; myosin binding; alpha-actinin binding. Biological Process: skeletal muscle development; positive regulation of actin filament polymerization; glomerular filtration; glomerular basement membrane development; MAPKKK cascade; JNK cascade; cell adhesion; myoblast fusion
size1 :
0.5 mg (E-Coli)
price1 :
715 USD
size2 :
0.5 mg (Yeast)
price2 :
950
size3 :
0.05 mg (Baculovirus)
price3 :
950
size4 :
1 mg (E-Coli)
price4 :
1170
size5 :
0.05 mg (Mammalian-Cell)
price5 :
1170
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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