protein

Human Prolactin-Induced Protein

MBS145461

0.002 mg

140 USD

Protein

Human Prolactin-Induced Protein

[Prolactin-Induced]

[PIP Human; Prolactin-Induced Protein Human; Prolactin-inducible protein; Gross cystic disease fluid protein 15; GCDFP-15; Prolactin-induced protein; Secretory actin-binding protein; SABP; gp17; PIP; GCDFP15; GPIP4]

[prolactin-inducible protein; Prolactin-inducible protein; prolactin-inducible protein; SABP; gross cystic disease fluid protein 15; secretory actin-binding protein; prolactin-induced protein; Gross cystic disease fluid protein 15; GCDFP-15; Prolactin-induced protein; Secretory actin-binding protein; SABP; gp17]

[PIP]

[PIP; PIP; GPIP4; GCDFP15; GCDFP-15; GCDFP15; GPIP4; GCDFP-15; SABP]

PIP_HUMAN

Human Seminal Plasma

146

QDNTRKIIIK NFDIPKSVRP NDEVTAVLAV QTELKECMVV KTYLISSIPL QGAFNYKYTA CLCDDNPKTF YWDFYTNRTV QIAAVVDVIR ELGICPDDAA VIPIKNNRFY TIEILKVE

Greater than 95% as determined by SDS-PAGE.

PIP protein filtered (0.4 um) and lyophilized in 0.5mg/ml in 0.05M phosphate buffer and 0.075M NaCl pH 8.0. Filtered White lyophilized (freeze-dried) powder.

Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4° for a limited period of time; it does not show any change after two weeks at 4°C.

Solubility: It is recommended to add deionized water to prepare a working stock solution of approximately 0.5 mg/ml and let the lyophilized pellet dissolve completely. PIP is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture. Human Virus Test: Samples from each donor have been tested and found negative for HBsAg, HIV1+2, HCV, syphilis, aHBc, RRR.

CYTOKINES AND GROWTH FACTORS; Growth Factors; Prolactin

Description: The Prolactin-Induced Protein produced from Human Seminal Plasma has a molecular mass of 13.52kDa (calculated without glycosylation) containing 118 amino acid residues. Introduction: Prolactin inducible protein (PIP) is a 17kDa glycoprotein existing in human seminal plasma. PIP is synthesized as a 146 amino acid long polypeptide exhibiting high sequence similarity with mouse submaxillary gland with a single glycosylation site. The precise biological functions of PIP are still ambiguous but various functions have been assigned to PIP due its existence at high concentration in biological fluids. PIP binds to various proteins such as fibrinogen, actin, keratin, myosin and tropomyosin. PIP is also expressed in pathological conditions of the mammary gland and in some exocrine tissues, such as the lacrimal, salivary and sweat glands. Due to PIP's association with secretory cell differentiation, it has been used in diagnostic evaluation of tumors of breast, salivary gland, and skin.

4505821

NP_002643.1

NM_002652.2

P12273

16,572 Da

PIP: Belongs to the PIP family. Protein type: Cytoskeletal; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 7q34. Cellular Component: extracellular space; apical plasma membrane; nucleus. Molecular Function: protein dimerization activity; protein binding; IgG binding; actin binding; aspartic-type endopeptidase activity; glycoprotein binding. Biological Process: retinal homeostasis; regulation of immune system process; detection of chemical stimulus involved in sensory perception of bitter taste; proteolysis

0.002 mg

140 USD

0.01 mg

205

0.1 mg

1220