catalog number :
MBS145438
products type :
Native Protein
products full name :
Human Adiponectin
products short name :
Adiponectin
products name syn :
Acrp30 Human; Adiponectin Human; Acrp30; AdipoQ; GBP-28; APM-1; ACDC
other names :
adiponectin; Adiponectin; adiponectin; 30 kDa adipocyte complement-related protein; adipocyte complement-related 30 kDa protein; adipose most abundant gene transcript 1 protein; adipose specific collagen-like factor; gelatin-binding protein 28; adiponectin, C1Q and collagen domain containing; 30 kDa adipocyte complement-related protein; Adipocyte complement-related 30 kDa protein; ACRP30; Adipocyte, C1q and collagen domain-containing protein; Adipose most abundant gene transcript 1 protein; apM-1; Gelatin-binding protein
products gene name :
Acrp30
other gene names :
ADIPOQ; ADIPOQ; ACDC; ADPN; APM1; APM-1; GBP28; ACRP30; ADIPQTL1; ACDC; ACRP30; APM1; GBP28; ACRP30; apM-1
uniprot entry name :
ADIPO_HUMAN
host :
Human Pooled Serum
sequence :
MLLLGAVLLL LALPGHDQET TTQGPGVLLP LPKGACTGWM AGIPGHPGHN GAPGRDGRDG TPGEKGEKGD PGLIGPKGDI GETGVPGAEG PRGFPGIQGR KGEPGEGAYV YRSAFSVGLE TYVTIPNMPI RFTKIFYNQQ NHYDGSTGKF HCNIPGLYYF AYHITVYMKD VKVSLFKKDK AMLFTYDQYQ ENNVDQASGS VLLHLEVGDQ VWLQVYGEGE RNGLYADNDN DSTFTGFLLY HDTN
form :
Acrp30 Human was filtered (0.05 um) and lyophilized from 0.5 mg/ml supplied in 20mM TRIS, 50mM NaCl and 1mM CaCl2, pH 7.5
storage stability :
Store lyophilized Acrp30 Human at -20 degree C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted Acrp30 Human can be stored at 4 degree C for a limited period of time; it does not show any change after two weeks at 4 degree C.
tested application :
ELISA (EIA), Immunological Methods, Western Blot (WB)
app notes :
Cell culture and/or animal studies, ELISA, Immunological methods and Western blotting
other info2 :
Patent Rights: The sale and/or commercial use of Recombinant Adiponectin is prohibited in the United States of America (U.S.A). Solubility: It is recommended to add deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it on cell culture. QC Test: BCA - to determine content of the protein. SDS PAGE - to determine purity of the protein.
products categories :
CYTOKINES AND GROWTH FACTORS; Cytokines; Adiponectin
products description :
Description: The Acrp30 Human protein contains 244 amino acid having a molecular mass of 26.42kDa. Native adiponectin is isolated from human pooled sera and contains all HMW, MMW and LMW fractions. Introduction: Adiponectin, also referred to as Acrp30, AdipoQ and GBP-28, is a recently discovered 244 amino acid protein, the product of the apM1 gene, which is physiologically active and specifically and highly expressed in adipose cells (Adipokine). The protein belongs to the soluble defense collagen super family; it has a collagen-like domain structurally homologous with collagen VIII and X and complement factor C1q-like globular domain. APM-1 forms homotrimers, which are the building blocks for higher order complexes found circulating in serum.
ncbi acc num :
NP_001171271.1
ncbi gb acc num :
NM_001177800.1
ncbi mol weight :
26,414 Da
ncbi pathways :
AMPK Signaling Pathway 198868!!AMPK Signaling Pathway 989139!!AMPK Signaling Pathway 992181!!Adipocytokine Signaling Pathway 83093!!Adipocytokine Signaling Pathway 505!!Adipogenesis Pathway 198832!!Developmental Biology Pathway 477129!!Non-alcoholic Fatty Liver Disease (NAFLD) Pathway 862188!!Non-alcoholic Fatty Liver Disease (NAFLD) Pathway 862314!!PPAR Signaling Pathway 83042
ncbi summary :
This gene is expressed in adipose tissue exclusively. It encodes a protein with similarity to collagens X and VIII and complement factor C1q. The encoded protein circulates in the plasma and is involved with metabolic and hormonal processes. Mutations in this gene are associated with adiponectin deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Apr 2010]