catalog number :
MBS145435
products type :
Native Protein
products full name :
Human Leucine-Rich Alpha-2-Glycoprotein 1
products short name :
Leucine-Rich Alpha-2-Glycoprotein 1
products name syn :
LRG1 Human; Leucine-Rich Alpha-2-Glycoprotein 1 Human; Leucine-rich alpha-2-glycoprotein; LRG; LRG1; FLJ45787; HMFT1766
other names :
leucine-rich alpha-2-glycoprotein; Leucine-rich alpha-2-glycoprotein; leucine-rich alpha-2-glycoprotein; 1300008B03Rik; 2310031E04Rik; leucine rich alpha 2 glycoprotein; leucine-rich alpha-2-glycoprotein 1
products gene name :
LRG1
other gene names :
LRG1; LRG1; LRG; HMFT1766; LRG; LRG
uniprot entry name :
A2GL_HUMAN
host :
Human Pooled Serum
sequence :
VTLSPKDCQV FRSDHGSSIS CQPPAEIPGY LPADTVHLAV EFFNLTHLPA NLLQGASKLQ ELHLSSNGLE SLSPEFLRPV PQLRVLDLTR NALTGLPPGL FQASATLDTL VLKENQLEVL EVSWLHGLKA LGHLDLSGNR LRKLPPGLLA NFTLLRTLDL GENQLETLPP DLLRGPLQLE RLHLEGNKLQ VLGKDLLLPQ PDLRYLFLNG NKLARVAAGA FQGLRQLDML DLSNNSLASVPEGLWASLGQ PNWDMRDGFD ISGNPWICDQ NLSDLYRWLQ AQKDKMFSQN DTRCAGPEAV KGQTLLAVAK SQ.
form :
LRG1 protein filtered (0.4 um) and lyophilized from 20mM Tris and 20mM NaCl, pH 8.
storage stability :
Store lyophilized protein at -20 degree C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4 degree C for a limited period of time; it does not show any change after two weeks at 4 degree C.
other info2 :
Solubility: It is recomended to add deionized water to prepare a working stock solution of approximately 0.5 mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture. Human Virus Test: Blood samples from each donor have been tested and found negative for HBsAg, anti-HCV, HIV Ag/Ab, and syphilis.
products categories :
RECOMBINANT & NATURAL PROTEINS; Natural Proteins
products description :
Description: The Human LRG1 produced from human pooled serum has a molecular mass of 34.35kDa (calculated without glycosylation) containing 312 amino acid residues. Introduction: LRG1 belongs to the leucine-rich repeat (LRR) family of proteins, which have been shown to be involved in protein-protein interaction, signal transduction, and cell adhesion and development. The LRG1 is expressed during granulocyte differentiation.
ncbi acc num :
NP_443204.1
ncbi gb acc num :
NM_052972.2
ncbi mol weight :
38,178 Da
ncbi summary :
The leucine-rich repeat (LRR) family of proteins, including LRG1, have been shown to be involved in protein-protein interaction, signal transduction, and cell adhesion and development. LRG1 is expressed during granulocyte differentiation (O'Donnell et al., 2002 [PubMed 12223515]).[supplied by OMIM, Mar 2008]
uniprot summary :
LRG1: . Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 19p13.3. Cellular Component: extracellular space; membrane; extracellular region. Molecular Function: transforming growth factor beta receptor binding. Biological Process: positive regulation of angiogenesis; brown fat cell differentiation; positive regulation of transforming growth factor beta receptor signaling pathway; positive regulation of endothelial cell proliferation