protein

Recombinant Human Leucine Carboxyl Methyltransferase 1

MBS145387

0.005 mg

140 USD

Recombinant Protein

Recombinant Human Leucine Carboxyl Methyltransferase 1

Leucine Carboxyl Methyltransferase 1

LCMT1 Human; Leucine Carboxyl Methyltransferase 1 Human Recombinant; Leucine carboxyl methyltransferase 1; Protein-leucine O-methyltransferase; [Phosphatase 2A protein]-leucine-carboxy methyltransferase 1; LCMT1; LCMT; PPMT1; CGI-68

leucine carboxyl methyltransferase 1 isoform b; Leucine carboxyl methyltransferase 1; leucine carboxyl methyltransferase 1; [Phosphatase 2A protein]-leucine-carboxy methyltransferase 1; protein phosphatase methyltransferase 1; protein-leucine O-methyltransferase; leucine carboxyl methyltransferase 1; Protein-leucine O-methyltransferase; [Phosphatase 2A protein]-leucine-carboxy methyltransferase 1

LCMT1

LCMT1; LCMT1; LCMT; PPMT1; CGI-68; LCMT

LCMT1_HUMAN

E Coli

279

Greater than 95.0% as determined by SDS-PAGE.

The LCMT1 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 10% glycerol, 1mM DTT and 0.15M NaCl. Sterile Filtered colorless solution.

ENZYMES; Enzymes; Transferase

Description: LCMT1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 358 amino acids (1-334) and having a molecular mass of 41kDa.LCMT1 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Introduction: LCMT1 is a member of the LCMT family, methyltransferase superfamily. LCMT1 catalyzes the methylation of the carboxyl group of the C-terminal leucine residue (leu309) of the catalytic subunit of protein phosphatase-2A to form alpha-leucine ester residues.

74048545

NP_001027563.1

NM_001032391.1

Q9UIC8

32,172 Da

LCMT1 catalyzes the methylation of the carboxyl group of the C-terminal leucine residue (leu309) of the catalytic subunit of protein phosphatase-2A (PPP2CA; MIM 176915) (De Baere et al., 1999 [PubMed 10600115]).[supplied by OMIM, Mar 2008]

LCMT1: Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues. Belongs to the methyltransferase superfamily. LCMT family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Amino Acid Metabolism - tyrosine; Amino Acid Metabolism - histidine; EC 2.1.1.233; Lipid Metabolism - androgen and estrogen; Methyltransferase; Other Amino Acids Metabolism - selenoamino acid. Chromosomal Location of Human Ortholog: 16p12.1. Cellular Component: cytosol. Molecular Function: protein binding; C-terminal protein carboxyl methyltransferase activity; S-adenosylmethionine-dependent methyltransferase activity. Biological Process: regulation of apoptosis; protein amino acid methylation; C-terminal protein amino acid methylation; protein modification process; negative regulation of protein complex assembly

0.005 mg

140 USD

0.02 mg

205

1 mg

2665