catalog number :
MBS145275
products type :
Recombinant Protein
products full name :
Recombinant Human Glutathione S-Transferase Theta-2
products short name :
Glutathione S-Transferase Theta-2
products name syn :
GSTT2 Human; Glutathione S-Transferase Theta-2 Human Recombinant; Glutathione S-transferase theta 2; GST class-theta-2; GSTT2B; Glutathione S-transferase theta-2B; EC 2.5.1.18
other names :
glutathione S-transferase theta-2 isoform a; Glutathione S-transferase theta-2; glutathione S-transferase theta-2; GST class-theta-2; glutathione S-transferase theta 2 (gene/pseudogene); GST class-theta-2
products gene name :
GSTT2
other gene names :
GSTT2; GSTT2
uniprot entry name :
GST2_HUMAN
purity :
Greater than 95% as determined by SDS-PAGE.
form :
The GSTT2 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 100mM Nacl, 1mM DTT and 10% glycerol. Sterile Filtered colorless solution.
products categories :
ENZYMES; Enzymes; Transferase
products description :
Description: GSTT2 Recombinant produced in E Coli is a single polypeptide chain containing 264 amino acids (1-244) and having a molecular mass of 29.6kDa.GSTT2 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
ncbi acc num :
NP_000845.2
ncbi gb acc num :
NM_000854.4
ncbi mol weight :
27,506 Da
ncbi pathways :
Biological Oxidations Pathway (105698); Chemical Carcinogenesis Pathway (673221); Chemical Carcinogenesis Pathway (673237); Defective AHCY Causes Hypermethioninemia With S-adenosylhomocysteine Hydrolase Deficiency (HMAHCHD) Pathway (1127639); Defective GCLC Causes Hemolytic Anemia Due To Gamma-glutamylcysteine Synthetase Deficiency (HAGGSD) Pathway (1127658); Defective GGT1 Causes Glutathionuria (GLUTH) Pathway (1127659); Defective GSS Causes Glutathione Synthetase Deficiency (GSS Deficiency) Pathway (1127660); Defective MAT1A Causes Methionine Adenosyltransferase Deficiency (MATD) Pathway (1127663); Defective OPLAH Causes 5-oxoprolinase Deficiency (OPLAHD) Pathway (1127661); Defective SLC35D1 Causes Schneckenbecken Dysplasia (SCHBCKD) Pathway (1127665)
ncbi summary :
Glutathione S-transferase (GSTs) theta 2 (GSTT2) is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: Alpha, Mu, Pi, Theta, and Zeta. The theta class members GSTT1 and GSTT2 share 55% amino acid sequence identity and both are thought to have an important role in human carcinogenesis. The theta genes have a similar structure, being composed of five exons with identical exon/intron boundaries. [provided by RefSeq, Jul 2008]
uniprot summary :
GST2: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a sulfatase activity. Belongs to the GST superfamily. Theta family. Protein type: EC 2.5.1.18. Chromosomal Location of Human Ortholog: 22q11.23. Cellular Component: cytoplasm. Molecular Function: glutathione transferase activity. Biological Process: metabolic process