product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Cyclin-B2
catalog :
MBS145143
quantity :
0.002 mg
price :
140 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS145143
products type :
Recombinant Protein
products full name :
Recombinant Human Cyclin-B2
products short name :
[Cyclin-B2]
products name syn :
[CCNB2 Human; Cyclin-B2 Human Recombinant; G2/mitotic-specific cyclin-B2; HsT17299; cyclin B2]
other names :
[G2/mitotic-specific cyclin-B2; G2/mitotic-specific cyclin-B2; G2/mitotic-specific cyclin-B2; cyclin B2]
products gene name :
[CCNB2]
other gene names :
[CCNB2; CCNB2; HsT17299]
uniprot entry name :
CCNB2_HUMAN
host :
E Coli
sequence length :
398
sequence :
MGSSHHHHHH SSGLVPRGSH MGSH MALLRR PTVSSDLENI DTGVNSKVKS HVTIRRTVLE EIGNRVTTRA AQVAKKAQNT KVPVQPTKTT NVNKQLKPTA SVKPVQMEKL APKGPSPTPE DVSMKEENLC QAFSDALLCK IEDIDNEDWE NPQLCSDYVK DIYQYLRQLE VLQSINPHFL DGRDINGRMR AILVDWLVQV HSKFRLLQET LYMCVGIMDR FLQVQPVSRK KLQLVGITAL LLASKYEEMF SPNIEDFVYI TDNAYTSSQI REMETLILKE LKFELGRPLP LHFLRRASKA GEVDVEQHTL AKYLMELTLI DYDMVHYHPS KVAAAASCLS QKVLGQGKWN LKQQYYTGYT ENEVLEVMQH MAKNVVKVNE NLTKFIAIKN KYASSKLLKI SMIPQLNSKA VKDLASPLIG RS
purity :
Greater than 90% as determined by SDS-PAGE.
form :
The CCNB2 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 5mM DTT and 50% glycerol.
storage stability :
Store at 4°C if entire vial will be used within 2-4 weeks. Store frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze/thaw cycles.
other info1 :
Physical Appearance: Sterile filtered colorless solution.
products categories :
PROTEIN KINASES; Enzymes; Cyclin
products description :
Description: CCNB2 Human Recombinant produced in E Coli is a single polypeptide chain containing 422 amino acids (1-398) and having a molecular mass of 47.9 kDa.CCNB2 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Introduction: CCNB2 is a member of the cyclin family. CCNB2 is vital for regulation of the cell cycle at the G2/M (mitosis) transition. CCNB2 cooperates with the CDK1 protein kinase to create a serine/threonine kinase holoenzyme complex recognized as maturation promoting factor (MPF).
ncbi gi num :
4757930
ncbi acc num :
NP_004692.1
ncbi gb acc num :
NM_004701.3
uniprot acc num :
O95067
ncbi mol weight :
45,282 Da
ncbi pathways :
Activation Of NIMA Kinases NEK9, NEK6, NEK7 Pathway (771571); Cell Cycle Pathway (530733); Cell Cycle Checkpoints Pathway (105739); Cell Cycle, Mitotic Pathway (105765); Cell Cycle Pathway (198811); Cell Cycle Pathway (83054); Cell Cycle Pathway (463); Cell Cycle - G2/M Transition Pathway (1084769); Cell Cycle - G2/M Transition Pathway (1108232); Condensation Of Prometaphase Chromosomes Pathway (730316)
ncbi summary :
Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control. [provided by RefSeq, Jul 2008]
uniprot summary :
CCNB2: Essential for the control of the cell cycle at the G2/M (mitosis) transition. Belongs to the cyclin family. Cyclin AB subfamily. Protein type: Cell cycle regulation. Chromosomal Location of Human Ortholog: 15q22.2. Cellular Component: nucleoplasm; microtubule cytoskeleton; centrosome; membrane; cytosol. Molecular Function: protein binding; protein kinase binding. Biological Process: mitosis; thymus development; regulation of cell cycle; cell division; in utero embryonic development; mitotic nuclear envelope disassembly; T cell homeostasis; regulation of cyclin-dependent protein kinase activity; mitotic cell cycle; G2/M transition of mitotic cell cycle; growth
size1 :
0.002 mg
price1 :
140 USD
size2 :
0.01 mg
price2 :
205
size3 :
1 mg
price3 :
5015
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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