catalog number :
MBS145060
products type :
Recombinant Protein
products full name :
Recombinant Rhesus Macaque Interleukin-3
products short name :
Interleukin-3
products name syn :
IL 3 Rhesus Macaque; Interleukin-3 Rhesus Macaque Recombinant; MCGF (Mast cell growth factor); Multi-CSF; HCGF; P-cell stimulation factor; IL-3; MGC79398; MGC79399
other names :
interleukin-3; Interleukin-3; interleukin-3; P-cell stimulating factor; P-cell-stimulating factor; colony-stimulating factor, multiple; hematopoietic growth factor; mast cell growth factor; mast-cell growth factor; multilineage-colony-stimulating factor; multipotential colony-stimulating factor; interleukin 3; Hematopoietic growth factor; Mast cell growth factor; MCGF; Multipotential colony-stimulating factor; P-cell-stimulating factor
products gene name :
rmIL3
other gene names :
IL3; IL3; IL-3; MCGF; MULTI-CSF; IL-3; MCGF
uniprot entry name :
IL3_HUMAN
sequence :
APMTQTTSLK TSWAKCSNMI DEIITHLNQP PLPSPDFNNL NEEDQTILVE KNLRRSNLEA FSKAVKSLQN ASAIESILKN LPPCLPMATA APTRPPIRIT NGDRNDFRRK LKFYLKTLEN EQAQ
purity :
Greater than 97.0% as determined by SDS-PAGE.
form :
Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4. Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
Lyophilized IL-3 Rhesus Macaque although stable at room temperature for 3 weeks, should be stored dessicated below -18 degree C. Upon reconstitution IL3 Rheus Macaque should be stored at 4 degree C between 2-7 days and for future use below -18 degree C. Please prevent freeze-thaw cycles.
other info2 :
Solubility: It is recommended to reconstitute the lyophilized IL-3 in sterile 18MOmega-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Biological Activity: The ED50 as determined by the dose-dependant stimulation of the proliferation of human TF-1 cells is less than 0.1ng/ml, corresponding to a Specific Activity of 10,000,000IU/mg.
products categories :
CYTOKINES AND GROWTH FACTORS; Cytokines; Interleukin
products description :
Description: IL 3 Rhesus Macaque Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 124 amino acids and having a molecular mass of 14.0kDa.The IL 3 Rhesus Macaque is purified by proprietary chromatographic techniques. Introduction: IL3 is a potent growth promoting cytokine. This cytokine is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. This cytokine has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.
ncbi acc num :
NP_000579.2
ncbi gb acc num :
NM_000588.3
ncbi mol weight :
17,233 Da
ncbi pathways :
Apoptosis Pathway 83060!!Apoptosis Pathway 470!!Asthma Pathway 83120!!Asthma Pathway 532!!Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway 137993!!Calcium Signaling In The CD4+ TCR Pathway 137941!!Cytokine Signaling In Immune System Pathway 366171!!Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!Fc Epsilon RI Signaling Pathway 83082
ncbi summary :
The protein encoded by this gene is a potent growth promoting cytokine. This cytokine is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. This cytokine has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders. [provided by RefSeq, Jul 2008]