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company name :
MyBioSource
product type :
protein
product name :
Recombinant Chikungunya Mutant (A226V) E1
catalog :
MBS144891
quantity :
0.002 mg
price :
140 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS144891
products type :
Recombinant Protein
products full name :
Recombinant Chikungunya Mutant (A226V) E1
products short name :
Chikungunya Mutant E1
products name syn :
CHIKV Mutant; Chikungunya Mutant (A226V) E1 Recombinant; CHIKV Mutant
other names :
Structural polyprotein, E2-6K-E1 region; Structural polyprotein, E2-6K-E1 region
products gene name :
CHIKV
other gene names :
E2-6K-E1
uniprot entry name :
G0LWX6_CHIKV
host :
Insect Cells
sequence length :
923
sequence :
YEHVTVIPNTVGVPYKTLVNRPGYSPMVLEMELLSVTLE
PTLSLDYITCEYKTVIPSPYVKCCGTAECKDKNLPDYSC
KVFTGVYPFMWGGAYCFCDAENTQLSEAHVEKSESCKTE
FASAYRAHTASASAKLRVLYQGNNITVTAYANGDHAVTV
KDAKFIVGPMSSAWTPFDNKIVVYKGDVYNMDYPPFGAG
RPGQFGDIQSRTPESKDVYANTQLVLQRPAVGTVHVPYS
QAPSGFKYWLKERGASLQHTAPFGCQIATNPVRAVNCAV
GNMPISIDIPEAAFTRVVDAPSLTDMSCEVPACTHSSDF
GGVAIIKYAASKKGKCAVHSMTNAVTIREAEIEVEGNSQ
LQISFSTALASAEFRVQVCSTQVHCAAECHPPKDHIVNY
PASHTTLGQDISATAMSWVQKITGG.
purity :
Protein is >=95% pure as determined by 12.5% SDS-PAGE
form :
CHIKV Mutant protein solution in 1xD-PBS, pH7.4, 0.1% Thimerosal, 5mM EDTA, 1 ug/ml of Leupeptin, Aprotinin and Pepstatin A. Sterile filtered colorless solution.
storage stability :
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
products categories :
VIRAL ANTIGENS- CHIKUNGUNYA VIRUS; Viral Antigens; Chikungunya
products description :
Description: Recombinant Chikungunya Mutant (A226V) E1 produced in Insect Cells is a polypeptide chain containing amino acids 1-415, however at position 226 the Alanine of the wild-type CHIKV E1 gene was mutated to Valine. The molecular weight of the CHIKV Mutant is approximately 50kDa. The E1 protein is C-terminal part of E2-6K-E1 protein region. CHIKV Mutant is purified by proprietary chromatographic technique. Introduction: Chikungunya virus (CHIKV) is an arthropod-born virus which is a member of the Alphavirus genus belonging to the Togaviridae family. CHIKV nucleocapsid is comprised of a single-stranded plussense RNA genome of approximately 11.8 kb. The CHIKV virion envelope consists of a lipid bilayer derived from the plasma membrane from the host cell, multiple copies of 2 major virus encoded glycoproteins E1 and E2, and a small 6K peptide. Proteins E1 and E2 both have a molecular weight of roughly 50kDa and form a heterodimer anchored in the membrane. Chikungunya virus infection causes an illness with symptoms similar to those of the dengue fever with an acute febrile phase lasting only 2-5 days, followed by a prolonged arthralgic disease affecting the joint extremities. Recent Chikungunya virus outbreaks presented a prospect for genetic analysis of patients with the illness, revealing a point mutation at the amino acid 226 (Ala mutated to Val) of the E1 gene. This point mutation was confirmed to be responsible for an improved capacity of CHIKV strains to infect and replicate in the Aedes albopictus, enabling virus transmission to a naive human population.
uniprot acc num :
G0LWX6
ncbi mol weight :
101,424 Da
size1 :
0.002 mg
price1 :
140 USD
size2 :
0.01 mg
price2 :
205
size3 :
1 mg
price3 :
5015
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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