product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Thioredoxin-interacting protein (TXNIP)
catalog :
MBS1448817
quantity :
0.05 mg (E-Coli)
price :
805 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1448817
products type :
Recombinant Protein
products full name :
Recombinant Human Thioredoxin-interacting protein (TXNIP)
products short name :
[Thioredoxin-interacting protein (TXNIP)]
other names :
[thioredoxin-interacting protein isoform 2; Thioredoxin-interacting protein; thioredoxin-interacting protein; thioredoxin interacting protein; Thioredoxin-binding protein 2; Vitamin D3 up-regulated protein 1]
products gene name :
[TXNIP]
products gene name syn :
[TXNIP]
other gene names :
[TXNIP; TXNIP; THIF; VDUP1; ARRDC6; HHCPA78; EST01027; VDUP1]
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
[1-391aa, full length protein]
sequence length :
336
sequence :
MVMFKKIKSFEVVFNDPEKVYGSGEKVAGRVIVEVCEVT
RVKAVRILACGVAKVLWMQGSQQCKQTSEYLRYEDTLLL
EDQPTGENEMVIMRPGNKYEYKFGFELPQGPLGTSFKGK
YGCVDYWVKAFLDRPSQPTQETKKNFEVVDLVDVNTPDL
MAPVSAKKEKKVSCMFIPDGRVSVSARIDRKGFCEGDEI
SIHADFENTCSRIVVPKAAIVARHTYLANGQTKVLTQKL
SSVRGNHIISGTCASWRGKSLRVQKIRPSILGCNILRVE
YSLLIYVSVPGSKKVILDLPLVIGSRSGLSSRTSSMASR
TSSEMSWVDLNIPDTPEAPPCYMDVIPEDHRLESPTTPL
LDDMDGSQDSPIFMYAPEFKFMPPPTYTEVDPCILNNNV
Q
purity :
>85% (SDS-PAGE)
form :
Liquid containing glycerol
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Human
other info2 :
Storage Buffer: Tris-based buffer, 50% glycerol
ncbi gi num :
928192549
ncbi acc num :
NP_001300901.1
ncbi gb acc num :
NM_001313972.1
uniprot acc num :
Q9H3M7
ncbi mol weight :
37,319 Da
ncbi pathways :
Immune System Pathway (1269170); Inflammasomes Pathway (1269253); Innate Immune System Pathway (1269203); NOD-like Receptor Signaling Pathway (122191); NOD-like Receptor Signaling Pathway (122131); Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor (NLR) Signaling Pathways (1269251); The NLRP3 Inflammasome Pathway (1269254)
ncbi summary :
This gene encodes a thioredoxin-binding protein that is a member of the alpha arrestin protein family. Thioredoxin is a thiol-oxidoreductase that is a major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
uniprot summary :
May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1).
size1 :
0.05 mg (E-Coli)
price1 :
805 USD
size2 :
0.05 mg (Yeast)
price2 :
890
size3 :
0.2 mg (E-Coli)
price3 :
1075
size4 :
0.05 mg (Baculovirus)
price4 :
1120
size5 :
0.5 mg (E-Coli)
price5 :
1185
size6 :
0.2 mg (Yeast)
price6 :
1205
size7 :
0.05 mg (Mammalian-Cell)
price7 :
1360
size8 :
0.5 mg (Yeast)
price8 :
1365
size9 :
0.1 mg (Baculovirus)
price9 :
1620
size10 :
1 mg (E-Coli)
price10 :
1795
size11 :
0.5 mg (Baculovirus)
price11 :
2110
size12 :
1 mg (Yeast)
price12 :
2170
size13 :
0.1 mg (Mammalian-Cell)
price13 :
2210
size14 :
1 mg (Baculovirus)
price14 :
3260
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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