catalog number :
MBS144787
products type :
Recombinant Protein
products full name :
Recombinant Mycobacterium Tuberculosis major secretory protein Antigen 85A
products short name :
Mycobacterium Tuberculosis major secretory protein Antigen 85A
products name syn :
Ag85A; Mycobacterium Tuberculosis major secretory protein Antigen 85A Recombinant; Ronectin-binding protein A; Mycolyl transferase 85A
products gene name :
Ag85A
purity :
Greater than 90% as determined by SDS-PAGE.
form :
The Ag85A solution (0.5mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0) and 10% glycerol. Sterile Filtered colorless solution.
products categories :
RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; Mycobacterium Tuberculosis major secretory protein Antigen
products description :
Description: Recombinant Mycobacterium tuberculosis Ag85A (43-338 a.a) produced in Hi-5 cells is a single, glycosylated polypeptide chain having a molecular mass of 32.8kDa (305 a.a in total).Antigen 85A is fused to a His tag at C-terminus and purified by conventional chromatographic techniques. Introduction: Antigen 85A is a member of the antigen 85 complex (Antigen 85A, B, C). The enzymes of the antigen 85 complex have mycolyltransferase activity and catalyze the synthesis of the very rich glycolipid of the mycobacterial cell wall, the cord factor (trehalose 6,6'-dimycolate, TDM). The cord factor is vital for the integrity of the mycobacterial cell wall and pathogenesis of the bacillus. TDM is synthesized from two molecules of trehalose-6'-monomycolate (TMM) by Antigen 85A.