catalog number :
MBS144717
products type :
Recombinant Protein
products full name :
Recombinant Human Peptidase Inhibitor 16
products short name :
[Peptidase Inhibitor 16]
products name syn :
[PI16 Human; Peptidase Inhibitor 16 Human Recombinant; Peptidase inhibitor 16; PI-16; Cysteine-rich secretory protein 9; CRISP-9; PSP94-binding protein; PI16; CRISP9; PSPBP; MSMBBP; MGC45378; DKFZp586B1817]
other names :
[peptidase inhibitor 16; Peptidase inhibitor 16; peptidase inhibitor 16; PSP94-binding protein; cysteine-rich secretory protein 9; microseminoprotein, beta-binding protein; protease inhibitor 16; peptidase inhibitor 16; Cysteine-rich secretory protein 9; CRISP-9; PSP94-binding protein]
products gene name :
[PI16]
other gene names :
[PI16; PI16; PSPBP; CRISP9; MSMBBP; CRISP9; PSPBP; PI-16; CRISP-9]
uniprot entry name :
PI16_HUMAN
sequence :
LTDEEKRLMV ELHNLYRAQV SPPASDMLHM RWDEELAAFA KAYARQCVWG HNKERGRRGE NLFAITDEGM DVPLAMEEWH HEREHYNLSA ATCSPGQMCG HYTQVVWAKT ERIGCGSHFC EKLQGVEETN IELLVCNYEP PGNVKGKRPY QEGTPCSQCP SGYHCKNSLC EPIGSPEDAQ DLPYLVTEAP SFRATEASDS RKMGTPSSLA TGIPAFLVTE VSGSLATKAL PAVETQAPTS LATKDPPSMA TEAPPCVTTE VPSILAAHSL PSLDEEPVTF PKSTHVPIPK SADKVTDKTK VPSRSPENSL DPKMSLTGAR ELLPHAQEEA EAEAELPPSS EVLASVFPAQ DKPGELQATL DHTGHTSSKS LPNFPNTSAT ANATGGRALA LQSSLPGAEG PDKPSVVSGL NSGPGAAADY KDDDDK
purity :
Greater than 95.0% as determined by SDS-PAGE
form :
PI16 was filtered (0.4 um) and lyophilized from 0.5mg/ml in 20mM Tris and 50mM NaCl, pH 7.5. Filtered White lyophilized (freeze-dried) powder.
storage stability :
Store lyophilized PI16 Human recombinant at -20 degree C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4 degree C for a limited period of time; it does not show any change after two weeks at 4 degree C.
other info2 :
Source: HEK293 (Human Embryonic Kidney cell line). Solubility: It is recommended to add deionized water to prepare a working stock solution of 0.5mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
products categories :
ENZYMES; Enzymes; Peptidase
products description :
Description: The Peptidase Inhibitor 16 Human Recombinant is produced in HEK293 cells and fused with a C-terminal Flag Tag (11 amino acids). The PI16 Flag Tagged Fusion Protein is 45.7kDa protein containing a total of 426 amino acid residues and purified by proprietary chromatographic techniques. Introduction: Peptidase Inhibitor 16 (PI16) which a member of the CRISP family, is a putative serine protease inhibitor. PI16 interacts with PSP94/MSMB. PI16 is expressed in the prostate, testis, ovary and intestine. It also concentrates in prostate cancer patient's sera. PI16 may serve as a marker following prostatectomy for prostate cancer.
ncbi acc num :
NP_001186088.1
ncbi gb acc num :
NM_001199159.1
ncbi mol weight :
29,674 Da
uniprot summary :
PI16: Putative serine protease inhibitor. Belongs to the CRISP family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 6p21.2. Cellular Component: extracellular space; integral to membrane. Molecular Function: protease inhibitor activity. Biological Process: negative regulation of peptidase activity