catalog number :
MBS1446879
products type :
Recombinant Protein
products full name :
Recombinant Human Procollagen C-endopeptidase enhancer 2 (PCOLCE2)
products short name :
[Procollagen C-endopeptidase enhancer 2 (PCOLCE2)]
products name syn :
[Procollagen COOH-terminal proteinase enhancer 2; PCPE-2; Procollagen C-proteinase enhancer 2]
other names :
[procollagen C-endopeptidase enhancer 2; Procollagen C-endopeptidase enhancer 2; procollagen C-endopeptidase enhancer 2; procollagen C-endopeptidase enhancer 2; Procollagen COOH-terminal proteinase enhancer 2; PCPE-2; Procollagen C-proteinase enhancer 2]
products gene name :
[PCOLCE2]
other gene names :
[PCOLCE2; PCOLCE2; PCPE2; PCPE2; PCPE-2; Procollagen C-proteinase enhancer 2]
uniprot entry name :
PCOC2_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
[24-415. Mature full length protein.]
sequence :
QSPERPVFTCGGILTGESGFIGSEGFPGVYPPNSKCTWK
ITVPEGKVVVLNFRFIDLESDNLCRYDFVDVYNGHANGQ
RIGRFCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAM
FSAAEPNERGDQYCGGLLDRPSGSFKTPNWPDRDYPAGV
TCVWHIVAPKNQLIELKFEKFDVERDNYCRYDYVAVFNG
GEVNDARRIGKYCGDSPPAPIVSERNELLIQFLSDLSLT
ADGFIGHYIFRPKKLPTTTEQPVTTTFPVTTGLKPTVAL
CQQKCRRTGTLEGNYCSSDFVLAGTVITTITRDGSLHAT
VSIINIYKEGNLAIQQAGKNMSARLTVVCKQCPLLRRGL
NYIIMGQVGEDGRGKIMPNSFIMMFKTKNQKLLDALKNK
QC
purity :
Greater than 90% as determined by SDS-PAGE.
form :
Liquid containing glycerol
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
image1 heading :
SDS-PAGE
other info2 :
Species: Homo sapiens (Human)
products categories :
Cell Biology
products description :
Binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1.
products references :
PCOLCE2 encodes a functional procollagen C-proteinase enhancer (PCPE2) that is a collagen-binding protein differing in distribution of expression and post-translational modification from the previously described PCPE1."
Steiglitz B.M., Keene D.R., Greenspan D.S.
J. Biol. Chem. 277:49820-49830(2002)
ncbi acc num :
NP_037495.1
ncbi gb acc num :
NM_013363.3
ncbi mol weight :
59.25kD
ncbi pathways :
Collagen Biosynthesis And Modifying Enzymes Pathway (1270246); Collagen Formation Pathway (1270245); Extracellular Matrix Organization Pathway (1270244)
uniprot summary :
PCOLCE2: Binds to the C-terminal propeptide of types I and II procollagens and may enhance the cleavage of that propeptide by BMP1. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 3q21-q24. Molecular Function: collagen binding; heparin binding; protease activator activity