product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human FGFR1 Oncogene Partner
catalog :
MBS144619
quantity :
0.01 mg
price :
205 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS144619
products type :
Recombinant Protein
products full name :
Recombinant Human FGFR1 Oncogene Partner
products short name :
FGFR1 Oncogene Partner
products name syn :
FGFR1OP Human; FGFR1 Oncogene Partner Human Recombinant; FGFR1 oncogene partner; FGFR1OP; FOP
other names :
FGFR1 oncogene partner isoform a; FGFR1 oncogene partner; FGFR1 oncogene partner; fibroblast growth factor receptor 1 oncogene partner; FGFR1 oncogene partner
products gene name :
FGFR1OP
other gene names :
FGFR1OP; FGFR1OP; FOP; FOP
uniprot entry name :
FR1OP_HUMAN
host :
E Coli
sequence length :
399
purity :
Greater than 85.0% as determined by SDS-PAGE.
form :
FGFR1OP protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 10% glycerol and 1mM DTT. Sterile filtered colorless solution.
products categories :
PROTEIN KINASES; Enzymes; FGF Receptors
products description :
Description: FGFR1OP Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 403 amino acids (1-379 a.a) and having a molecular mass of 43.5kDa.FGFR1OP is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Introduction: FGFR1 oncogene partner (FGFR1OP) is a member of the FGFR1OP family. The FGFR1OP protein is an essentially hydrophilic protein proposed to be a leucine-rich protein family member. A t(6;8)(q27;p11) chromosomal translocation, fusing the FGFR1OP gene and the FGFR1 gene, is seen in cases of myeloproliferative disorder. The ensuing chimeric protein contains the N-terminal leucine-rich region of the FGFR1OP protein fused to the catalytic domain of FGFR1. The FGFR1OP gene is believed to play a significant role in normal proliferation and differentiation of the erythroid lineage.
ncbi gi num :
5901954
ncbi acc num :
NP_008976.1
ncbi gb acc num :
NM_007045.3
uniprot acc num :
O95684
ncbi mol weight :
16,106 Da
ncbi pathways :
Anchoring Of The Basal Body To The Plasma Membrane Pathway 1127503!!Assembly Of The Primary Cilium Pathway 1127502!!Cell Cycle Pathway 530733!!Cell Cycle, Mitotic Pathway 105765!!Centrosome Maturation Pathway 105807!!Disease Pathway 530764!!G2/M Transition Pathway 105801!!Loss Of Nlp From Mitotic Centrosomes Pathway 105811!!Loss Of Proteins Required For Interphase Microtubule Organizationfrom The Centrosome Pathway 105810!!Mitotic G2-G2/M Phases Pathway 160942
ncbi summary :
This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified. [provided by RefSeq, Jul 2013]
size :
0.01 mg
price :
205 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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