protein

Recombinant Human AIG2-Like Domain 1

MBS144470

0.002 mg

140 USD

Recombinant Protein

Recombinant Human AIG2-Like Domain 1

AIG2-Like Domain 1

A2LD1 Human; AIG2-Like Domain 1 Human Recombinant; Gamma-glutamylaminecyclotransferase; GGACT; AIG2-like domain-containing protein 1; A2LD1

gamma-glutamylaminecyclotransferase; Gamma-glutamylaminecyclotransferase; gamma-glutamylaminecyclotransferase; AIG2-like domain 1; AIG2-like domain-containing protein 1; gamma-glutamylamine cyclotransferase; AIG2-like domain-containing protein 1; Gamma-glutamylamine cyclotransferase

A2LD1

GGACT; GGACT; A2LD1; A2LD1; GGACT

GGACT_HUMAN

E Coli

153

Greater than 95.0% as determined by SDS-PAGE.

The A2LD1 solution (1 mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 10% glycerol and 0.1M NaCl. Sterile Filtered colorless solution.

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins

Introduction: Gamma-glutamylaminecyclotransferase (A2LD1) is an enzyme which converts gamma-glutamylamines to free amines and 5-oxoproline. A2LD1 demonstrates high activity toward gamma-glutamyl-epsilon-lysine, derived from the breakdown of fibrin and other proteins cross-linked by transglutaminases. A2LD1 assists in the proteolytic degradation of crosslinked fibrin by breaking down isodipeptide L-gamma-glutamyl-L-epsilon-lysine, which is a byproduct of fibrin degradation. The reaction catalyzed by the A2LD1 produces 5-oxo-L-proline and a free alkylamine.

304284846

NP_001182016.1

NM_001195087.1

Q9BVM4

17,329 Da

The protein encoded by this gene aids in the proteolytic degradation of crosslinked fibrin by breaking down isodipeptide L-gamma-glutamyl-L-epsilon-lysine, a byproduct of fibrin degradation. The reaction catalyzed by the encoded gamma-glutamylaminecyclotransferase produces 5-oxo-L-proline and a free alkylamine. Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Aug 2010]

A2LD1: Contributes to degradation of proteins cross-linked by transglutaminases. Degrades the cross-link between a lysine and a glutamic acid residue from two proteins that have been cross- linked by transglutaminases. Catalyzes the formation of 5- oxoproline from L-gamma-glutamyl-L-epsilon-lysine. Inactive with L-gamma-glutamyl-alpha-amino acid substrates such as L-gamma- glutamyl-L-alpha-cysteine and L-gamma-glutamyl-L-alpha-alanine. Belongs to the gamma-glutamylcyclotransferase family. Protein type: Transferase; EC 2.3.2.4. Chromosomal Location of Human Ortholog: 13q32.3. Molecular Function: gamma-glutamylcyclotransferase activity. Biological Process: amino acid derivative catabolic process

0.002 mg

140 USD

0.01 mg

205

1 mg

5015