Recombinant Human Syntaxin-4 | MyBioSource MBS144465 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Human Syntaxin-4

catalog :

MBS144465

quantity :

0.005 mg

price :

140 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS144465

products type :

Recombinant Protein

products full name :

Recombinant Human Syntaxin-4

products short name :

[Syntaxin-4]

products name syn :

[Syntaxin 4, syntaxin 4A (placental), STX4A, Renal carcinoma antigen NY-REN-31, p35-2.]

other names :

[syntaxin-4 isoform 2; Syntaxin-4; syntaxin-4; renal carcinoma antigen NY-REN-31; syntaxin 4A (placental); syntaxin 4; Renal carcinoma antigen NY-REN-31]

products gene name :

[STX4]

other gene names :

[STX4; STX4; STX4A; p35-2; STX4A]

uniprot entry name :

STX4_HUMAN

host :

E Coli

sequence length :

295

sequence :

MGSSHHHHHH SSGLVPRGSH MGSHM MRDRT HELRQGDDSS DEEDKERVAL VVHPGTARLG SPDEEFFHKV RTIRQTIVKL GNKVQELEKQ QVTILATPLP EESMKQELQN LRDEIKQLGR EIRLQLKAIE PQKEEADENY NSVNTRMRKT QHGVLSQQFV ELINKCNSMQ SEYREKNVER IRRQLKITNA GMVSDEELEQ MLDSGQSEVF VSNILKDTQV TRQALNEISA RHSEIQQLER SIRELHDIFT FLATEVEMQG EMINRIEKNI LSSADYVERG QEHVKTALEN QKKARKKKVL

purity :

Greater than 90% as determined by SDS-PAGE.

form :

The STX4 solution (1mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 100mM NaCl, 1mM DTT and 40% glycerol.

storage stability :

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

other info1 :

Physical Appearance: The STX4 solution (1mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 100mM NaCl, 1mM DTT and 40% glycerol.

products categories :

RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; Syntaxin

products description :

Description: STX4 Human Recombinant produced in E Coli is a single polypeptide chain containing 300 amino acids (1-275) and having a molecular mass of 34.7 kDa.STX4 is fused to a 25 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Introduction: Syntaxin 4 (STX4) is a member of the syntaxin/epimorphin family of proteins. The Syntaxin family is cellular receptors for transport vesicles which participate in exocytosis in neutrophils. Syntaxin 4 is vital for normal insulin-stimulated glucose uptake in skeletal muscle and decline in STX4 protein levels lead to reduction of whole-body insulin-stimulated glucose metabolism. STX4 is expressed in neutrophils and neutrophil-differentiated HL-60 cells. The STX4 expression in neutrophils increases with differentiation.

ncbi gi num :

443287677

ncbi acc num :

NP_001259025.1

ncbi gb acc num :

NM_001272096.1

uniprot acc num :

Q12846

ncbi pathways :

Clathrin Derived Vesicle Budding Pathway (119545); Disinhibition Of SNARE Formation Pathway (106049); Hemostasis Pathway (106028); Insulin Signaling Pathway (198845); Insulin-mediated Glucose Transport Pathway (137981); Membrane Trafficking Pathway (106160); Platelet Activation, Signaling And Aggregation Pathway (106034); Response To Elevated Platelet Cytosolic Ca2+ Pathway (106048); SNARE Interactions In Vesicular Transport Pathway (83057); SNARE Interactions In Vesicular Transport Pathway (467)

uniprot summary :

STX4: a protein of the syntaxin/epimorphin family. Contains 1 t-SNARE coiled-coil homology domain. Potentially involved in docking of synaptic vesicles at presynaptic active zones. Interacts with SNAP23 and SNAP25BP. Found in a complex with VAMP8 and SNAP23 in pancreas. Protein type: Membrane protein, integral; Vesicle. Chromosomal Location of Human Ortholog: 16p11.2. Cellular Component: extracellular space; specific granule; cell surface; lateral loop; basolateral plasma membrane; integral to membrane; dendritic spine; trans-Golgi network; cytosol; SNARE complex; synaptic vesicle; membrane; lamellipodium; perinuclear region of cytoplasm; plasma membrane; vacuole; synapse; intracellular; endosome. Molecular Function: SNAP receptor activity; sphingomyelin phosphodiesterase activator activity; SNARE binding; protein binding. Biological Process: positive regulation of catalytic activity; platelet activation; positive regulation of cell adhesion; organelle fusion; positive regulation of eosinophil degranulation; positive regulation of chemotaxis; positive regulation of immunoglobulin secretion; regulation of exocytosis; synaptic vesicle fusion to presynaptic membrane; intracellular protein transport; vesicle docking; response to hydroperoxide; positive regulation of cell proliferation; post-Golgi vesicle-mediated transport; blood coagulation; positive regulation of cell migration

size1 :

0.005 mg

price1 :

140 USD

size2 :

0.02 mg

price2 :

205

size3 :

1 mg

price3 :

2665

more info or order :

MyBioSource product webpage