product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Phosphohistidine Phosphatase 1
catalog :
MBS144317
quantity :
0.005 mg
price :
140 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS144317
products type :
Recombinant Protein
products full name :
Recombinant Human Phosphohistidine Phosphatase 1
products short name :
Phosphohistidine Phosphatase 1
products name syn :
PHPT1 Human; Phosphohistidine Phosphatase 1 Human Recombinant; PHP14; CGI-202; HSPC141; Phosphohistidine Phosphatase 1; Phosphohistidine Phosphatase 14kDa; Protein janus-A homolog; Sex-regulated protein Janus-a
other names :
14 kDa phosphohistidine phosphatase isoform 2; 14 kDa phosphohistidine phosphatase; 14 kDa phosphohistidine phosphatase; epididymis secretory sperm binding protein Li 132P; protein janus-A homolog; sex-regulated protein janus-a; phosphohistidine phosphatase 1; Phosphohistidine phosphatase 1; Protein janus-A homolog
products gene name :
PHPT1
other gene names :
PHPT1; PHPT1; PHP14; CGI-202; HSPC141; HEL-S-132P; PHP14
uniprot entry name :
PHP14_HUMAN
host :
E Coli
sequence length :
124
sequence :
MGSSHHHHHH SSGLVPRGSH MAVADLALIP DVDIDSDGVF KYVLIRVHSA PRSGAPAAES KEIVRGYKWA EYHADIYDKV SGDMQKQGCD CECLGGGRIS HQSQDKKIHV YGYSMAYGPA QHAISTEKIK AKYPDYEVTW ANDGY
purity :
Greater than 95% as determined by SDS-PAGE.
form :
The PHPT1 protein solution (0.5mg/1ml) is formulated in 20 mM Tris-HCl buffer (pH8.0) 0.2M NaCl, 2mM DTT and 10% glycerol. Sterile Filtered colorless solution.
storage stability :
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time.For long term storage it is recommended to add a carrier protien (0.1% HSA or BSA).Please avoid freeze thaw cycles.
products categories :
ENZYMES; Enzymes; Phosphatase
products description :
Description: PHPT1 produced in E Coli is a single, non-glycosylated polypeptide chain containing 145 amino acids (1-125a.a.) and having a molecular mass of 15.9kDa.PHPT1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Introduction: PHPT1 is a member of the Janus protein familyand is 125 amino acid long. PHPT1 appears as a monomer in the cytoplasm and is an EDTA-insensitive phosphohistidine phosphatase. Overexpression of PHPT1 resolts in specific phosphohistidine phosphatase activity towards phosphopeptide I, with no activity detected towards phosphotyrosine, phosphothreonine and phosphoserine peptides.
ncbi gi num :
209529723
ncbi acc num :
NP_001129333.1
ncbi gb acc num :
NM_001135861.2
uniprot acc num :
Q9NRX4
ncbi mol weight :
13,672 Da
ncbi pathways :
Fructose And Mannose Metabolism Pathway (82930); Fructose And Mannose Metabolism Pathway (291)
ncbi summary :
This gene encodes an enzyme that catalyzes the reversible dephosphorylation of histidine residues in proteins. It may be involved in the dephosphorylation of G-beta and ATP citrate lyase and in negatively regulating CD4 T lymphocytes by dephosphorylation and inhibition of KCa3.1 channels. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
uniprot summary :
PHPT1: a phosphohistidine phosphatase. Present preferentially in heart and skeletal muscle. Insensitive to inhibition by okadaic acid and EDTA. Protein type: Motility/polarity/chemotaxis; Cofactor and Vitamin Metabolism - thiamine; EC 3.1.3.-; Carbohydrate Metabolism - fructose and mannose; Phosphatase; Cofactor and Vitamin Metabolism - riboflavin. Chromosomal Location of Human Ortholog: 9q34.3. Cellular Component: cytosol. Molecular Function: phosphohistidine phosphatase activity; calcium channel inhibitor activity; phosphoprotein phosphatase activity. Biological Process: negative regulation of lyase activity; negative regulation of T cell receptor signaling pathway; protein amino acid dephosphorylation
size1 :
0.005 mg
price1 :
140 USD
size2 :
0.025 mg
price2 :
205
size3 :
1 mg
price3 :
2665
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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