protein

Recombinant Human Acidic Nuclear Phosphoprotein 32 Family, Member A

MBS144301

0.002 mg

140 USD

Recombinant Protein

Recombinant Human Acidic Nuclear Phosphoprotein 32 Family, Member A

Acidic Nuclear Phosphoprotein 32 Family

ANP32A Human; Acidic Nuclear Phosphoprotein 32 Family Member A Human Recombinant; I1PP2A; LANP; MAPM; PHAP1; Leucine-rich acidic nuclear protein; PP32; Mapmodulin

acidic leucine-rich nuclear phosphoprotein 32 family member A; Acidic leucine-rich nuclear phosphoprotein 32 family member A; acidic leucine-rich nuclear phosphoprotein 32 family member A; acidic nuclear phosphoprotein pp32; cerebellar leucine rich acidic nuclear protein; hepatopoietin Cn; inhibitor-1 of protein phosphatase-2A; leucine-rich acidic nuclear protein; mapmodulin; potent heat-stable protein phosphatase 2A inhibitor I1PP2A; putative HLA-DR-associated protein I; putative human HLA class II associated protein I; acidic (leucine-rich) nuclear phosphoprotein 32 family, member A; Acidic nuclear phosphoprotein pp32; pp32; Leucine-rich acidic nuclear protein; LANP; Mapmodulin; Potent heat-stable protein phosphatase 2A inhibitor I1PP2A; Putative HLA-DR-associated protein I; PHAPI

ANP32A

ANP32A; ANP32A; LANP; MAPM; PP32; HPPCn; PHAP1; PHAPI; I1PP2A; C15orf1; C15orf1; LANP; MAPM; PHAP1; pp32; LANP; PHAPI

AN32A_HUMAN

E Coli

249

MGSSHHHHHH SSGLVPRGSH MEMGRRIHLE LRNRTPSDVK ELVLDNSRSN EGKLEGLTDE FEELEFLSTI NVGLTSIANL PKLNKLKKLE LSDNRVSGGL EVLAEKCPNL THLNLSGNKI KDLSTIEPLK KLENLKSLDL FNCEVTNLND YRENVFKLLP QLTYLDGYDR DDKEAPDSDA EGYVEGLDDE EEDEDEEEYD EDAQVVEDEE DEDEEEEGEE EDVSGEEEED EEGYNDGEVD DEEDEEELGE EERGQKRKRE PEDEGEDDD

Greater than 90% as determined by SDS-PAGE.

ANP32A solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 100mM NaCl, 0.1mM PMSF and 10% glycerol. Sterile filtered colorless solution.

ANP32A Human Recombinant although stable at 4 degree C for 1 week, should be stored below -18 degree C. Please prevent freeze thaw cycles.

RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins

Description: ANP32A Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 269amino acids (1-249a.a.) and having a molecular mass of 30.7kDa. ANP32A is fused to 20 amino acid His Tag at N-terminus and purified by proprietary chromatographic techniques. Introduction: ANP32A often cooperate with MAP1B, TAF1A and Protein SET. ANP32A is involved in several cellular processes, such as proliferation, differentiation, caspase-dependent and caspase-independent apoptosis. Mapmodulin takes a part in E4F1-mediated transcriptional repression.

5453880

NP_006296.1

NM_006305.3

P39687

28,585 Da

Gene Expression Pathway (105937); HuR Stabilizes MRNA Pathway (187216); Regulation Of MRNA Stability By Proteins That Bind AU-rich Elements Pathway (187211)

ANP32A: Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase- independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability in association with ELAVL1, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex. Plays a role in E4F1- mediated transcriptional repression. Belongs to the ANP32 family. Protein type: Nuclear receptor co-regulator; Transcription, coactivator/corepressor. Chromosomal Location of Human Ortholog: 15q23. Cellular Component: nucleoplasm; endoplasmic reticulum; perinuclear region of cytoplasm; cytoplasm; nucleus. Molecular Function: protein binding. Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; gene expression; nucleocytoplasmic transport

0.002 mg

140 USD

0.01 mg

205

1 mg

5015