catalog number :
MBS144273
products type :
Recombinant Protein
products full name :
Recombinant Human Microtubule-Associated Protein, RP/EB Family, Member 3
products short name :
Microtubule-Associated
products name syn :
MAPRE3 Human; Microtubule-Associated Protein, RP/EB Family, Member 3 Human Recombinant; RP3; EB3; EBF3; End-binding protein 3; EBF3-S; APC binding protein
other names :
microtubule-associated protein RP/EB family member 3; Microtubule-associated protein RP/EB family member 3; microtubule-associated protein RP/EB family member 3; APC binding protein; EB1 protein family member 3; end-binding protein 3; microtubule-associated protein, RP/EB family, member 3; EB1 protein family member 3; EBF3; End-binding protein 3; EB3; RP3
products gene name :
MAPRE3
other gene names :
MAPRE3; MAPRE3; EB3; RP3; EBF3; EBF3-S; EBF3; EB3
uniprot entry name :
MARE3_HUMAN
sequence :
MGSSHHHHHH SSGLVPRGSH MAVNVYSTSV TSENLSRHDM LAWVNDSLHL NYTKIEQLCS GAAYCQFMDM LFPGCVHLRK VKFQAKLEHE YIHNFKVLQA AFKKMGVDKI IPVEKLVKGK FQDNFEFIQW FKKFFDANYD GKDYNPLLAR QGQDVAPPPN PGDQIFNKSK KLIGTAVPQR TSPTGPKNMQ TSGRLSNVAP PCILRKNPPS ARNGGHETDA QILELNQQLV DLKLTVDGLE KERDFYFSKL RDIELICQEH ESENSPVISG IIGILYATEE GFAPPEDDEI EEHQQEDQDE Y
purity :
Greater than 90% as determined by SDS-PAGE.
form :
The MAPRE3 protein solution (1mg/1ml) is formulated in 20mM Tris-HCl buffer (pH 8.0) 2mM DTT, 0.1M NaCl and 10% glycerol. Sterile Filtered clear solution.
storage stability :
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time.Please avoid freeze thaw cycles.
products categories :
RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; Microtubule-Associated Protein
products description :
Description: MAPRE3 produced in E Coli is a single, non-glycosylated polypeptide chain containing 301 amino acids (1-281a.a.) and having a molecular mass of 34.1kDa.MAPRE3 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Introduction: MAPRE3 is a microtubule related protein that cooperates with the colorectal adenomatous polyposis coli tumor suppressor protein and takes a curtail part in regulating microtubule dynamics, cell polarity, and chromosome stability. MAPRE3 protein is related to MAPRE1 and also associates with the microtubule cytoskeleton. MAPRE3 is expressed mainly in the central nervous system and specially associates with APCL, a homolog of the adenomatous polyposis coli tumor suppressor protein.
ncbi acc num :
NP_036458.2
ncbi gb acc num :
NM_012326.3
ncbi mol weight :
30,380 Da
ncbi summary :
The protein encoded by this gene is a member of the RP/EB family of genes. The protein localizes to the cytoplasmic microtubule network and binds APCL, a homolog of the adenomatous polyposis coli tumor suppressor gene. [provided by RefSeq, Jul 2008]