catalog number :
MBS144247
products type :
Recombinant Protein
products full name :
Recombinant Human Glucosamine-Phosphate N-Acetyltransferase 1
products short name :
Glucosamine-Phosphate N-Acetyltransferase 1
products name syn :
GNPNAT1 Human; Glucosamine-Phosphate N-Acetyltransferase 1 Human Recombinant; Gpnat1; GNPNAT; GNA1; EC 2.3.1.4; FLJ10607; Glucosamine-Phosphate N-Acetyltransferase 1; Phosphoglucosamine acetylase; Phosphoglucosamine transacetylase; Glucosamine 6-Phosphate N-Acetyltransferase
other names :
glucosamine 6-phosphate N-acetyltransferase; Glucosamine 6-phosphate N-acetyltransferase; glucosamine 6-phosphate N-acetyltransferase; phosphoglucosamine acetylase; phosphoglucosamine transacetylase; glucosamine-phosphate N-acetyltransferase 1; Phosphoglucosamine acetylase; Phosphoglucosamine transacetylase
products gene name :
GNPNAT1
other gene names :
GNPNAT1; GNPNAT1; GNPNAT; Gpnat1; GNA1
uniprot entry name :
GNA1_HUMAN
sequence :
MGSSHHHHHH SSGLVPRGSH MGSMKPDETP MFDPSLLKEV DWSQNTATFS PAISPTHPGE GLVLRPLCTA DLNRGFFKVL GQLTETGVVS PEQFMKSFEH MKKSGDYYVT VVEDVTLGQI VATATLIIEH KFIHSCAKRG RVEDVVVSDE CRGKQLGKLL LSTLTLLSKK LNCYKITLEC LPQNVGFYKK FGYTVSEENY MCRRFLK
purity :
Greater than 90% as determined by SDS-PAGE.
form :
The GNPNAT1 protein solution (0.5mg/1ml) is formulated in 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 0.1M NaCl and 30% glycerol. Sterile Filtered clear solution.
storage stability :
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time.Please avoid freeze thaw cycles.
products categories :
ENZYMES; Enzymes; Transferase
products description :
Description: GNPNAT1 produced in E Coli is a single, non-glycosylated polypeptide chain containing 207 amino acids (1-184a.a.) and having a molecular mass of 23.1KDa.GNPNAT1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Introduction: GNPNAT1 is a member of the GNA1 subfamily of the larger acetyltransferase family of proteins. GNPNAT1 is limited to the Golgi apparatus and the endosome. GNPNAT1 is vital for UDPGlcNAc biosynthesis pathway. GNPNAT1 catalyzes the synthesis of GlcNAc6P from AcCoA and GlcN6P, a step in the UDP-GlcNAc6P formation pathway.
ncbi acc num :
NP_932332.1
ncbi gb acc num :
NM_198066.3
ncbi mol weight :
20,749 Da
ncbi pathways :
Amino Sugar And Nucleotide Sugar Metabolism Pathway 82979!!Amino Sugar And Nucleotide Sugar Metabolism Pathway 350!!Asparagine N-linked Glycosylation Pathway 161013!!Biosynthesis Of The N-glycan Precursor (dolichol Lipid-linked Oligosaccharide, LLO) And Transfer To A Nascent Protein Pathway 161014!!Defective ALG1 Causes ALG1-CDG (CDG-1k) Pathway 1127605!!Defective ALG11 Causes ALG11-CDG (CDG-1p) Pathway 1127608!!Defective ALG12 Causes ALG12-CDG (CDG-1g) Pathway 1127601!!Defective ALG14 Causes Congenital Myasthenic Syndrome (ALG14-CMS) Pathway 1127613!!Defective ALG2 Causes ALG2-CDG (CDG-1i) Pathway 1127603!!Defective ALG3 Causes ALG3-CDG (CDG-1d) Pathway 1127599