Recombinant Human Uridine-Cytidine Kinase 2 | MyBioSource MBS144227 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Human Uridine-Cytidine Kinase 2

catalog :

MBS144227

quantity :

0.005 mg

price :

140 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS144227

products type :

Recombinant Protein

products full name :

Recombinant Human Uridine-Cytidine Kinase 2

products short name :

Uridine-Cytidine Kinase 2

products name syn :

UCK2 Human; Uridine-Cytidine Kinase 2 Human Recombinant; UK; UCK 2; Uridine-Cytidine Kinase 2; Uridine Monophosphate Kinase; Cytidine Monophosphokinase 2

other names :

uridine-cytidine kinase 2; Uridine-cytidine kinase 2; uridine-cytidine kinase 2; cytidine monophosphokinase 2; testis-specific protein TSA903; uridine kinase; uridine monophosphate kinase; uridine monophosphokinase 2; uridine-cytidine kinase 2; Cytidine monophosphokinase 2; Testis-specific protein TSA903; Uridine monophosphokinase 2

products gene name :

UCK2

other gene names :

UCK2; UCK2; UK; UMPK; TSA903; UMPK; UCK 2

uniprot entry name :

UCK2_HUMAN

host :

E Coli

sequence length :

261

sequence :

MAGDSEQTLQ NHQQPNGGEP FLIGVSGGTA SGKSSVCAKI VQLLGQNEVD YRQKQVVILS QDSFYRVLTS EQKAKALKGQ FNFDHPDAFD NELILKTLKE ITEGKTVQIP VYDFVSHSRK EETVTVYPAD VVLFEGILAF YSQEVRDLFQ MKLFVDTDAD TRLSRRVLRD ISERGRDLEQ ILSQYITFVK PAFEEFCLPT KKYADVIIPR GADNLVAINL IVQHIQDILN GGPSKRQTNG CLNGYTPSRK RQASESSSRP HLEHHHHHH

purity :

Greater than 90% as determined by SDS-PAGE.

form :

The UCK2 protein solution (1mg/1ml) is formulated in 20mM Tris-HCl buffer (pH8.0), 2mM DTT, 100mM NaCl, 0.1mM PMSF, 1mM EDTA and 20% glycerol. Sterile Filtered clear solution.

storage stability :

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time.Please avoid freeze thaw cycles.

products categories :

PROTEIN KINASES; Enzymes; Protein Kinases

products description :

Description: UCK2 produced in E Coli is a single, non-glycosylated polypeptide chain containing 269 amino acids (1-261a.a.) and having a molecular mass of 30.3kDa.UCK2 is fused to an 8 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques. Introduction: UCK2 is a member of the uridinekinase family. UCK2 catalyzes the phosphorylation of uridine monophosphate to uridine diphosphate and cytidine monophosphate. UCK2 has a part in the production of pyrimidine nucleoside triphosphates essential for RNA and DNA synthesis. Furthermore, an allele of this gene is an important player in mediating nonhumoral immunity to Hemophilus influenzae type B.

ncbi gi num :

18699734

ncbi acc num :

NP_036606.2

ncbi gb acc num :

NM_012474.4

uniprot acc num :

Q9BZX2

ncbi mol weight :

12,587 Da

ncbi pathways :

Drug Metabolism - Other Enzymes Pathway (83033); Drug Metabolism - Other Enzymes Pathway (428); Fluoropyrimidine Activity Pathway (198778); Metabolic Pathways (132956); Metabolism Pathway (477135); Metabolism Of Nucleotides Pathway (106263); Pyrimidine Metabolism Pathway (106281); Pyrimidine Metabolism Pathway (82946); Pyrimidine Metabolism Pathway (309); Pyrimidine Salvage Reactions Pathway (106284)

ncbi summary :

This gene encodes a pyrimidine ribonucleoside kinase. The encoded protein (EC 2.7.1.48) catalyzes phosphorylation of uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP), respectively.[provided by RefSeq, Oct 2010]

uniprot summary :

UCK2: Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. Does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Can use ATP or GTP as a phosphate donor. Can also phosphorylate cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4- thiouridine, 5-bromouridine, N(4)-acetylcytidine, N(4)- benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5- methylcytidine, and N(4)-anisoylcytidine. Belongs to the uridine kinase family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: EC 2.7.1.48; Nucleotide Metabolism - pyrimidine; Kinase, other; Xenobiotic Metabolism - drug metabolism - other enzymes. Chromosomal Location of Human Ortholog: 1q23. Cellular Component: intracellular membrane-bound organelle; cytosol. Molecular Function: nucleoside kinase activity; uridine kinase activity; ATP binding. Biological Process: pyrimidine base metabolic process; nucleobase, nucleoside and nucleotide metabolic process; CMP salvage; pyrimidine nucleoside salvage; feeding behavior; response to axon injury; phosphorylation

size1 :

0.005 mg

price1 :

140 USD

size2 :

0.025 mg

price2 :

205

size3 :

1 mg

price3 :

2665

more info or order :

MyBioSource product webpage