protein

Recombinant Human GrpE-Like 1

MBS144224

0.002 mg

140 USD

Recombinant Protein

Recombinant Human GrpE-Like 1

GrpE-Like 1

GRPEL1 Human; GrpE-Like 1 Human Recombinant; HMGE; GrpE-like protein cochaperone; GREPEL1; FLJ25609

grpE protein homolog 1, mitochondrial; GrpE protein homolog 1, mitochondrial; grpE protein homolog 1, mitochondrial; GrpE-like protein cochaperone; mt-GrpE#1; GrpE-like 1, mitochondrial (E. coli); HMGE; Mt-GrpE#1

GRPEL1

GRPEL1; GRPEL1; HMGE; GREPEL1

GRPE1_HUMAN

E Coli

217

Greater than 90% as determined by SDS-PAGE.

The GRPEL1 protein solution (1mg/1ml) is formulated in 20mM Tris-HCl buffer (pH8.0), 0.2M NaCl, 1mM DTT and 10% glycerol. Sterile Filtered clear solution.

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.

RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins

Description: GRPEL1 produced in E Coli is a single, non-glycosylated polypeptide chain containing 211 amino acids (28-217a.a.) and having a molecular mass of 23.6kDa.GRPEL1 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Introduction: GRPEL1 is a vital component of the PAM complex, a complex necessary for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. GRPEL1 protein controls the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins.

24308295

NP_079472.1

NM_025196.2

Q9HAV7

24,279 Da

Metabolism Of Proteins Pathway (106230); Mitochondrial Protein Import Pathway (576261)

GRPEL1: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Belongs to the GrpE family. Protein type: Mitochondrial; Chaperone. Chromosomal Location of Human Ortholog: 4p16. Cellular Component: mitochondrion; mitochondrial matrix. Molecular Function: protein homodimerization activity; adenyl-nucleotide exchange factor activity; chaperone binding; unfolded protein binding. Biological Process: cellular protein metabolic process; protein folding; regulation of catalytic activity; protein targeting to mitochondrion

0.002 mg

140 USD

0.01 mg

205

1 mg

5015