Recombinant Human Acetyl-COA Acyltransferase | MyBioSource MBS144152 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Human Acetyl-COA Acyltransferase

catalog :

MBS144152

quantity :

0.005 mg

price :

140 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS144152

products type :

Recombinant Protein

products full name :

Recombinant Human Acetyl-COA Acyltransferase

products short name :

Acetyl-COA Acyltransferase

products name syn :

ACAA1 Human; Acetyl-COA Acyltransferase Human Recombinant; ACAA; PTHIO; THIO

other names :

3-ketoacyl-CoA thiolase, peroxisomal isoform b; 3-ketoacyl-CoA thiolase, peroxisomal; 3-ketoacyl-CoA thiolase, peroxisomal; acetyl-Coenzyme A acyltransferase 1; beta-ketothiolase; peroxisomal 3-oxoacyl-CoA thiolase; peroxisomal 3-oxoacyl-Coenzyme A thiolase; acetyl-CoA acyltransferase 1; Acetyl-CoA acyltransferase; Beta-ketothiolase; Peroxisomal 3-oxoacyl-CoA thiolase

products gene name :

ACAA1

other gene names :

ACAA1; ACAA1; ACAA; THIO; PTHIO; ACAA; PTHIO

uniprot entry name :

THIK_HUMAN

host :

E Coli

sequence length :

331

sequence :

MGSSHHHHHH SSGLVPRGSH MLSGAPQASA ADVVVVHGRR TAICRAGRGG FKDTTPDELL SAVMTAVLKD VNLRPEQLGD ICVGNVLQPG AGAIMARIAQ FLSDIPETVP LSTVNRQCSS GLQAVASIAG GIRNGSYDIG MACGVESMSL ADRGNPGNIT SRLMEKEKAR DCLIPMGITS ENVAERFGIS REKQDTFALA SQQKAARAQS KGCFQAEIVP VTTTVHDDKG TKRSITVTQD EGIRPSTTME GLAKLKPAFK KDGSTTAGNS SQVSDGAAAI LLARRSKAEE LGLPILGVLR SYAVVGVPPD IMGIGPAYAI PVALQKAGLT VSDVDIFEIN EAFASQAAYC VEKLRLPPEK VNPLGGAVAL GHPLGCTGAR QVITLLNELK RRGKRAYGVV SMCIGTGMGA AAVFEYPGN.

purity :

Greater than 95.0% as determined by SDS-PAGE.

form :

ACAA1 1mg/ml protein solution contains 20mM Tris pH-8, 0.1M NaCl, 1mM DTT & 20% glycerol. Sterile Filtered clear solution.

storage stability :

ACAA1 Human although stable at 4 degree C for 1 week, should be stored below -18 degree C. Please prevent freeze thaw cycles.

products categories :

ENZYMES; Enzymes; Transferase

products description :

Description: ACAA1 Recombinant Human produced in E Coli is a single, non-glycosylated polypeptide chain containing 419 amino acids (27-424 a.a.) and having a molecular mass of 43.8 kDa. The ACAA1 is fused to 21 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. Introduction: ACAA1 is part of the thiolase family of enzymes and is takes part in lipid metabolism. ACAA1 enzyme is localized to the peroxisome and catalyzes the conversion of acyl-CoA and acetyl-CoA to 3-oxoacyl-CoA in the fatty acid oxidation pathway. ACAA1 shows high enzymatic activity in liver, kidney, intestine and white adipose tissue in rats. ACAA1 deficiency causes pseudo-Zellweger syndrome.

ncbi gi num :

194353979

ncbi acc num :

NP_001123882.1

ncbi gb acc num :

NM_001130410.1

ncbi mol weight :

34,665 Da

ncbi pathways :

Beta-oxidation Of Very Long Chain Fatty Acids Pathway (106139); Biosynthesis Of Unsaturated Fatty Acids Pathway (83034); Biosynthesis Of Unsaturated Fatty Acids Pathway (429); Fatty Acid Degradation Pathway (82935); Fatty Acid Degradation Pathway (296); Fatty Acid Metabolism Pathway (868084); Fatty Acid Metabolism Pathway (878045); Metabolic Pathways (132956); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976)

ncbi summary :

This gene encodes an enzyme operative in the beta-oxidation system of the peroxisomes. Deficiency of this enzyme leads to pseudo-Zellweger syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]

uniprot summary :

ACAA1: an enzyme operative in the beta-oxidation system of the peroxisomes. Deficiency of this enzyme leads to pseudo-Zellweger syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]. Protein type: Acetyltransferase; Lipid Metabolism - fatty acid; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Lipid Metabolism - unsaturated fatty acid biosynthesis; EC 2.3.1.16. Chromosomal Location of Human Ortholog: 3p22.2. Cellular Component: peroxisomal matrix; membrane; intracellular membrane-bound organelle; peroxisome. Molecular Function: palmitoyl-CoA oxidase activity; protein binding; acetyl-CoA C-acyltransferase activity. Biological Process: fatty acid beta-oxidation using acyl-CoA oxidase; fatty acid beta-oxidation; bile acid metabolic process; very-long-chain fatty acid metabolic process; unsaturated fatty acid metabolic process; cellular lipid metabolic process. Disease: D-bifunctional Protein Deficiency

size1 :

0.005 mg

price1 :

140 USD

size2 :

0.02 mg

price2 :

205

size3 :

1 mg

price3 :

2665

more info or order :

MyBioSource product webpage