catalog number :
MBS144129
products type :
Recombinant Protein
products full name :
Recombinant Human Galectin-2
products short name :
Galectin-2
products name syn :
LGALS2 Human; Galectin-2 Human Recombinant; HL14; Gal-2; Beta-galactoside-binding lectin L-14-II; Lactose-binding lectin 2; S-Lac lectin 2
other names :
galectin-2; Galectin-2; galectin-2; S-Lac lectin 2; beta-galactoside-binding lectin L-14-II; gal-2; galectin 2; lactose-binding lectin 2; lectin, galactoside-binding, soluble, 2; Beta-galactoside-binding lectin L-14-II; HL14; Lactose-binding lectin 2; S-Lac lectin 2
products gene name :
LGALS2
other gene names :
LGALS2; LGALS2; HL14; Gal-2
uniprot entry name :
LEG2_HUMAN
sequence :
MGSSHHHHHH SSGLVPRGSH MTGELEVKNM DMKPGSTLKI TGSIADGTDG FVINLGQGTD KLNLHFNPRF SESTIVCNSL DGSNWGQEQR EDHLCFSPGS EVKFTVTFES DKFKVKLPDG HELTFPNRLG HSHLSYLSVR GGFNMSSFKL KE.
purity :
Greater than 95.0% as determined by SDS-PAGE.
form :
The Galectin-2 His tag 0.5mg/ml protein solution contains 20mM Tris-HCl pH-8, 0.2M NaCl, 10% glycerol & 1mM DTT. Sterile Filtered colorless solution.
products categories :
CYTOKINES AND GROWTH FACTORS; Growth Factors; Galectin
products description :
Description: LGALS2 Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 152 amino acids (1-132 a.a.) and having a molecular mass of 16.8 kDa. The LGALS2 is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. Introduction: LGALS2 is a soluble beta-galactoside binding lectin that controls cell-to-cell adhesion and cell-to-extracellular matrix interactions and takes part in tumor progression, pre-mRNA splicing and apoptosis. LGALS2 induces apoptosis in activated T cells and binds to the cytokine lymphotoxin-alpha (LTA) with threat of myocardial infarction.
ncbi acc num :
NP_006489.1
ncbi gb acc num :
NM_006498.2
ncbi mol weight :
14,644 Da
ncbi summary :
The protein encoded by this gene is a soluble beta-galactoside binding lectin. The encoded protein is found as a homodimer and can bind to lymphotoxin-alpha. A single nucleotide polymorphism in an intron of this gene can alter the transcriptional level of the protein, with a resultant increased risk of myocardial infarction. [provided by RefSeq, Jul 2008]
uniprot summary :
LGALS2: This protein binds beta-galactoside. Its physiological function is not yet known. Chromosomal Location of Human Ortholog: 22q13.1. Molecular Function: galactoside binding; carbohydrate binding. Disease: Myocardial Infarction, Susceptibility To