product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Tryptophanyl-tRNA Synthetase
catalog :
MBS144071
quantity :
1 mg
price :
2665 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS144071
products type :
Recombinant Protein
products full name :
Recombinant Human Tryptophanyl-tRNA Synthetase
products short name :
Tryptophanyl-tRNA Synthetase
products name syn :
WARS Human; Tryptophanyl-tRNA Synthetase Human Recombinant; GAMMA-2; IFI53; IFP53; WRS; WARS; TrpRS; hWRS; EC=6.1.1.2; Tryptophanyl-tRNA synthetase; Interferon-induced protein 53; Tryptophan--tRNA ligase; GAMMA-2
other names :
tryptophan--tRNA ligase, cytoplasmic isoform a; Tryptophan--tRNA ligase, cytoplasmic; tryptophan--tRNA ligase, cytoplasmic; hWRS; interferon-induced protein 53; trpRS; tryptophan tRNA ligase 1, cytoplasmic; tryptophanyl-tRNA synthetase; Interferon-induced protein 53; IFP53; Tryptophanyl-tRNA synthetase; TrpRS; hWRS
products gene name :
WARS
other gene names :
WARS; WARS; IFI53; IFP53; GAMMA-2; IFI53; WRS; IFP53; TrpRS; hWRS
uniprot entry name :
SYWC_HUMAN
host :
E Coli
sequence length :
471
purity :
Greater than 90.0% as determined by SDS-PAGE.
form :
1mg/ml solution containing 20mM Tris-HCl pH-8, 1mM DTT, 0.1M NaCl, 1mM DTT & 10% glycerol. Sterile filtered colorless solution.
products categories :
ENZYMES; Enzymes; Synthetase
products description :
Description: WARS Recombinant Human produced in E Coli is a single, non-glycosylated polypeptide chain containing 491 amino acids (1-471 a.a.) and having a molecular mass of 55.3 kDa. The WARS is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. Introduction: WARS is part of the class I tRNA synthetase family. 2 types of tryptophanyl tRNA synthetase exist, a cytoplasmic form, called WARS, and a mitochondrial form, called WARS2. WARS catalyzes the aminoacylation of tRNA(trp) with tryptophan and is induced by interferon. WARS controls ERK, Akt, and eNOS activation pathways that are related with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression.
ncbi gi num :
47419914
ncbi acc num :
NP_004175.2
ncbi gb acc num :
NM_004184.3
uniprot acc num :
P23381
ncbi mol weight :
48,852 Da
ncbi pathways :
Aminoacyl-tRNA Biosynthesis Pathway 83030!!Aminoacyl-tRNA Biosynthesis Pathway 424!!Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway 413439!!Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway 468360!!Cytosolic TRNA Aminoacylation Pathway 105981!!Gene Expression Pathway 105937!!Tryptophan Metabolism Pathway 198850!!TRNA Aminoacylation Pathway 105980
ncbi summary :
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA(trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
size :
1 mg
price :
2665 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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