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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Sulfotransferase Family, Cytosolic, 2B, Member 1
catalog :
MBS144060
quantity :
1 mg
price :
2220 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS144060
products type :
Recombinant Protein
products full name :
Recombinant Human Sulfotransferase Family, Cytosolic, 2B, Member 1
products short name :
Sulfotransferase Family
products name syn :
SULT2B1 Human; Sulfotransferase Family, Cytosolic, 2B, Member 1 Human Recombinant; SULT2B1; HSST2; EC 2.8.2.2; Sulfotransferase 2B1; Hydroxysteroid sulfotransferase 2; ST2B1; Sulfotransferase family cytosolic 2B member 1
other names :
sulfotransferase family cytosolic 2B member 1 isoform a; Sulfotransferase family cytosolic 2B member 1; sulfotransferase family cytosolic 2B member 1; ST2B1; alcohol sulfotransferase; hydroxysteroid sulfotransferase 2; sulfotransferase 2B1; sulfotransferase family, cytosolic, 2B, member 1; Alcohol sulfotransferase; Hydroxysteroid sulfotransferase 2
products gene name :
SULT2B1
other gene names :
SULT2B1; SULT2B1; HSST2; HSST2; ST2B1; Sulfotransferase 2B1
uniprot entry name :
ST2B1_HUMAN
host :
E Coli
sequence length :
350
sequence :
MDGPAEPQIP GLWDTYEDDI SEISQKLPGE YFRYKGVPFP VGLYSLESIS LAENTQDVRD DDIFIITYPK SGTTWMIEII CLILKEGDPS WIRSVPIWER APWCETIVGA FSLPDQYSPR LMSSHLPIQI FTKAFFSSKA KVIYMGRNPR DVVVSLYHYS KIAGQLKDPG TPDQFLRDFL KGEVQFGSWF DHIKGWLRMK GKDNFLFITY EELQQDLQGS VERICGFLGR PLGKEALGSV VAHSTFSAMK ANTMSNYTLL PPSLLDHRRG AFLRKGVCGD WKNHFTVAQS EAFDRAYRKQ MRGMPTFPWD EDPEEDGSPD PEPSPEPEPK PSLEPNTSLE REPRPNSSPS PSPGQASETP HPRPS.
purity :
Greater than 85% as determined by SDS-PAGE.
form :
(SULT2B1 Human solution containing 20mM Trsi HCL pH-7.5, & 10% glycerol. Sterile filtered colorless solution.
storage stability :
SULT2B1 Human although stable at 4 degree C for 1 week, should be stored desiccated below -18 degree C. Please prevent freeze thaw cycles.
products categories :
ENZYMES; Enzymes; Transferase
products description :
Description: SULT2B1 Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 365 amino acids (1-365 a.a.) and having a molecular mass of 41.3 kDa. SULT2B1 protein is purified by standard chromatography. Introduction: SULT2B1 catalyzes the sulfate conjugation of numerous hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation enhances the water solubility of molecules, and therefore their renal excretion, however it can also result in bioactivation to form active metabolites. SULT2B1b is localized in the cytosol and nuclei of human cells. SULT2B1b is selective for the sulfation of 3beta-hydroxysteroids such as dehydroepiandrosterone and pregnenolone, and participates in cholesterol sulfation in human skin.
ncbi gi num :
31563388
ncbi acc num :
NP_004596.2
ncbi gb acc num :
NM_004605.2
uniprot acc num :
O00204
ncbi mol weight :
39,599 Da
ncbi pathways :
Biological Oxidations Pathway 105698!!Cytosolic Sulfonation Of Small Molecules Pathway 105724!!Defective AHCY Causes Hypermethioninemia With S-adenosylhomocysteine Hydrolase Deficiency (HMAHCHD) Pathway 1127639!!Defective GCLC Causes Hemolytic Anemia Due To Gamma-glutamylcysteine Synthetase Deficiency (HAGGSD) Pathway 1127658!!Defective GGT1 Causes Glutathionuria (GLUTH) Pathway 1127659!!Defective GSS Causes Glutathione Synthetase Deficiency (GSS Deficiency) Pathway 1127660!!Defective MAT1A Causes Methionine Adenosyltransferase Deficiency (MATD) Pathway 1127663!!Defective OPLAH Causes 5-oxoprolinase Deficiency (OPLAHD) Pathway 1127661!!Defective SLC35D1 Causes Schneckenbecken Dysplasia (SCHBCKD) Pathway 1127665!!Defective TPMT Causes Thiopurine S-methyltransferase Deficiency (TPMT Deficiency) Pathway 1127666
ncbi summary :
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene sulfates dehydroepiandrosterone but not 4-nitrophenol, a typical substrate for the phenol and estrogen sulfotransferase subfamilies. Two alternatively spliced variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]
size :
1 mg
price :
2220 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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