protein

Recombinant Human Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein Alpha

MBS144053

1 mg

2220 USD

Recombinant Protein

Recombinant Human Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein Alpha

Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein Alpha

SGTA Human; Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein Alpha Human Recombinant; alphaSGT; hSGT; SGT; Vpu-binding protein; UBP; Small glutamine-rich tetratricopeptide repeat-containing protein alpha; Alpha-SGT; SGT1

small glutamine-rich tetratricopeptide repeat-containing protein alpha; Small glutamine-rich tetratricopeptide repeat-containing protein alpha; small glutamine-rich tetratricopeptide repeat-containing protein alpha; UBP; alpha-SGT; protein containing three tetratricopeptide repeats; vpu-binding protein; small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha; Alpha-SGT; Vpu-binding protein; UBP

SGTA

SGTA; SGTA; SGT; hSGT; alphaSGT; SGT; SGT1; UBP

SGTA_HUMAN

E Coli

313

MDNKKRLAYA IIQFLHDQLR HGGLSSDAQE SLEVAIQCLE TAFGVTVEDS DLALPQTLPE IFEAAATGKE MPQDLRSPAR TPPSEEDSAE AERLKTEGNE QMKVENFEAA VHFYGKAIEL NPANAVYFCN RAAAYSKLGN YAGAVQDCER AICIDPAYSK AYGRMGLALS SLNKHVEAVA YYKKALELDP DNETYKSNLK IAELKLREAP SPTGGVGSFD IAGLLNNPGF MSMASNLMNN PQIQQLMSGM ISGGNNPLGT PGTSPSQNDL ASLIQAGQQF AQQMQQQNPE LIEQLRSQIR SRTPSASNDD QQELEHHHHH H.

Greater than 95% as determined by SDS-PAGE.

SGTA Human solution containing 20mM Trsi HCL pH-8, 1mM DTT and 10% glycerol. Sterile filtered colorless solution.

SGTA human although stable at 4 degree C for 1 week, should be stored desiccated below -18 degree C. Please prevent freeze thaw cycles.

RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins

Description: SGTA Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 321 amino acids (1-313 a.a.) and having a molecular mass of 35.1 kDa. SGTA protein is fused to a 8 amino acid His-Tag at C-terminus and purified by standard chromatography. Introduction: SGTA is a ubiquitously expressed protein that contains three TPR protein-protein interaction duplicates. SGTA takes part as a component of the androgen receptor (AR)-chaperone-cochaperone complex, functions as a cochaperone and participates in androgen signaling. SGTA binds directly to HSC70 and HSP70 and mediates their ATPase activity. SGTA gene encodes a protein that is able to interact with the chief nonstructural protein of parvovirus H-1 and 70-kDa heat shock cognate. In addition, SGTA interacts with Vpu and Gag from HIV-1, SARS-CoV accessory protein 7a, DNAJC5 and DNAJC5B. Since this transcript is expressed universally in several tissues, SGTA serves a housekeeping function. While being involved in apoptosis and androgen signaling, SGTA is a possible molecule for polycystic ovary syndrome, a disorder characterized by androgen excess, obesity and menstrual disturbances.

4506921

NP_003012.1

NM_003021.3

O43765

34,063 Da

This gene encodes a protein which is capable of interacting with the major nonstructural protein of parvovirus H-1 and 70-kDa heat shock cognate protein; however, its function is not known. Since this transcript is expressed ubiquitously in various tissues, this protein may serve a housekeeping function. [provided by RefSeq, Jul 2008]

1 mg

2220 USD