catalog number :
MBS144051
products type :
Recombinant Protein
products full name :
Recombinant Human Secretory Leukocyte Peptidase Inhibitor
products short name :
Secretory Leukocyte Peptidase Inhibitor
products name syn :
SLPI Human; Secretory Leukocyte Peptidase Inhibitor Human Recombinant; Antileukoproteinase; ALK1; ALP; BLPI; HUSI; HUSI-I; MPI; WAP4; WFDC4; WAP four-disulfide core domain protein 4; Protease inhibitor WAP4; Seminal proteinase inhibitor; Mucus proteinase inhibitor
other names :
antileukoproteinase; Antileukoproteinase; antileukoproteinase; HUSI-1; WAP four-disulfide core domain protein 4; mucus proteinase inhibitor; protease inhibitor WAP4; secretory leukocyte protease inhibitor (antileukoproteinase); seminal proteinase inhibitor; secretory leukocyte peptidase inhibitor; BLPI; HUSI-1; Mucus proteinase inhibitor; MPI; Protease inhibitor WAP4; Secretory leukocyte protease inhibitor; Seminal proteinase inhibitor; WAP four-disulfide core domain protein 4
products gene name :
SLPI
other gene names :
SLPI; SLPI; ALP; MPI; ALK1; BLPI; HUSI; WAP4; WFDC4; HUSI-I; WAP4; WFDC4; ALP; MPI
uniprot entry name :
SLPI_HUMAN
purity :
Greater than 80.0% as determined by SDS-PAGE.
form :
SLPI Human solution containing 20mM Tris-HCl pH-8.0, 2mM DTT, 0.1M NaCl & 20% glycerol. Sterile filtered colorless solution.
storage stability :
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
products categories :
RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins
products description :
Description: SLPI Recombinant E Coli produced in E Coli is a single, non-glycosylated polypeptide chain containing 128 amino acids (26-132 a.a.) and having a molecular mass of 14 kDa. The SLPI is fused to a 21 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. Introduction: SLPI is a secreted inhibitor which guards epithelial tissues from serine proteases. SLPI is localized in various secretions including seminal plasma, cervical mucus, and bronchial secretions, and has affinity for trypsin, leukocyte elastase, and cathepsin G. SLPI inhibitory effect contributes to the immune response by protecting epithelial surfaces from attack by endogenous proteolytic enzymes. SLPI protein has broad-spectrum anti-biotic activity. SLPI is an acid-stable proteinase inhibitor with strong affinities for trypsin, chymotrypsin, elastase, and cathepsin G. SLPI prevents elastase-mediated damage to oral and mucosal tissues.
ncbi acc num :
NP_003055.1
ncbi gb acc num :
NM_003064.3
ncbi mol weight :
14,326 Da
ncbi summary :
This gene encodes a secreted inhibitor which protects epithelial tissues from serine proteases. It is found in various secretions including seminal plasma, cervical mucus, and bronchial secretions, and has affinity for trypsin, leukocyte elastase, and cathepsin G. Its inhibitory effect contributes to the immune response by protecting epithelial surfaces from attack by endogenous proteolytic enzymes. This antimicrobial protein has antibacterial, antifungal and antiviral activity. [provided by RefSeq, Nov 2014]