protein

Recombinant Human S100 Calcium Binding Protein P, His Tag

MBS144050

0.005 mg

140 USD

Recombinant Protein

Recombinant Human S100 Calcium Binding Protein P, His Tag

[S100 Calcium Binding Protein P]

[Protein S100-E, S100E, Migration-Inducing Gene 9, MIG9]

[protein S100-P; Protein S100-P; protein S100-P; S100 calcium-binding protein P; migration-inducing gene 9 protein; protein S100-E; S100 calcium binding protein P; Migration-inducing gene 9 protein; MIG9; Protein S100-E; S100 calcium-binding protein P]

[S100P]

[S100P; S100P; MIG9; S100E; MIG9]

S100P_HUMAN

95

MGSSHHHHHH SSGLVPRGSH MTELETAMGM IIDVFSRYSG SEGSTQTLTK GELKVLMEKE LPGFLQSGKD KDAVDKLLKD LDANGDAQVD FSEFIVFVAA ITSACHKYFE KAGLK

Greater than 90.0% as determined by SDS-PAGE.

S100P Human solution containing 20mM Trsi HCL pH-8, 1mM DTT, 0.05M NaCl & 20% glycerol.

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

Source: E.coli. Physical Appearance: Sterile filtered colorless solution.

RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; Calcium Binding Protein

Description: S100P Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 115 amino acids (1-95a.a.) and having a molecular mass of 12.6 kDa. S100P protein is fused to a 20 amino acid His tag at N-terminus and is purified by standard chromatography. Introduction: S100P is a Ca2+ binding protein that is part of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are found in the cytoplasm and/or nucleus of a large range of cells, and participates in the regulation of a number of cellular function such as cell cycle progression and differentiation. S100P participates in numerous biological functions but the exact functions or mechanism of its action is still mostly unknown. Once S100P binds calcium ions it goes through a conformational change that results in an exposure of a hydrophobic surface which permits the interaction with specific target proteins.

5174663

NP_005971.1

NM_005980.2

P25815

10,400 Da

Gastric Cancer Network 1 Pathway (760635)

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 4p16. This protein, in addition to binding Ca2+, also binds Zn2+ and Mg2+. This protein may play a role in the etiology of prostate cancer. [provided by RefSeq, Jul 2008]

S100P: Homodimer. Interacts with S100PBP and S100Z. Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias. Belongs to the S-100 family. Chromosomal Location of Human Ortholog: 4p16. Cellular Component: microvillus membrane; cytoplasm; nucleus. Molecular Function: RAGE receptor binding; protein binding; magnesium ion binding; calcium ion binding; calcium-dependent protein binding. Biological Process: response to organic substance; endothelial cell migration

0.005 mg

140 USD

0.025 mg

205

1 mg

2235