protein

Recombinant Human S100 Calcium Binding Protein A8

MBS144048

0.02 mg

205 USD

Recombinant Protein

Recombinant Human S100 Calcium Binding Protein A8

S100 Calcium Binding Protein A8

S100A8 Human; S100 Calcium Binding Protein A8 Human Recombinant; Calgranulin A; MRP8; CAGA; CGLA; CFAG; Protein S100-A8; S100 calcium-binding protein A8; Migration inhibitory factor-related protein 8; MRP-8; p8; Cystic fibrosis antigen; Leukocyte L1 complex light chain; Calprotectin L1L subunit; Urinary stone protein band A; S100A8; MIF; NIF; L1Ag; CP-10; MA387; 60B8AG

protein S100-A8; Protein S100-A8; protein S100-A8; MRP-8; S100 calcium-binding protein A8 (calgranulin A); calgranulin-A; calprotectin L1L subunit; cystic fibrosis antigen; leukocyte L1 complex light chain; migration inhibitory factor-related protein 8; urinary stone protein band A; S100 calcium binding protein A8; Calgranulin-A; Calprotectin L1L subunit; Cystic fibrosis antigen; CFAG; Leukocyte L1 complex light chain; Migration inhibitory factor-related protein 8; MRP-8; p8; S100 calcium-binding protein A8; Urinary stone protein band AProtein S100-A8, N-terminally processed

S100A8

S100A8; S100A8; P8; MIF; NIF; CAGA; CFAG; CGLA; L1Ag; MRP8; CP-10; MA387; 60B8AG; CAGA; CFAG; MRP8; CFAG; MRP-8; p8

S10A8_HUMAN

E Coli

93

MLTELEKALN SIIDVYHKYS LIKGNFHAVY RDDLKKLLET ECPQYIRKKG ADVWFKELDI NTDGAVNFQE FLILVIKMGV AAHKKSHEES HKE.

Greater than 90% as determined by SDS-PAGE.

The S100A8 solution contains 20mM Tris-HCl pH-8, 1mM DTT, and 10% glycerol. Sterile Filtered clear colorless solution.

RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; Calcium Binding Protein

Description: S100A8 Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 93 amino acids (1-93 a.a.) and having a molecular mass of 10.8 kDa. The S100A8 is purified by proprietary chromatographic techniques. Introduction: S100A8 is a part of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a broad range of cells, and participate in the regulation of cellular processes such as cell cycle progression and differentiation. S100A8 plays a role in the inhibition of casein kinase and as a cytokine. S100A8 altered expression is related with cystic fibrosis disease. S100A8 is a calcium-binding protein that has antimicrobial activity against bacteria and fungi.S100A8 is crucial for resistance towards invasion by pathogenic bacteria. S100A8 up-regulates transcription of genes that are under the control of NF-kappa-B. S100A8 plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide. S100A8 endorses tubulin polymerization and promotes phagocyte migration and infiltration of granulocytes at sites of wounding. S100A8 takes part as a pro-inflammatory mediator in acute and chronic inflammation and up-regulates the release of IL8 and cell-surface expression of ICAM1.

21614544

NP_002955.2

NM_002964.4

P05109

10,835 Da

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. [provided by RefSeq, Jul 2008]

0.02 mg

205 USD