product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Hydroxyacyl-Coenzyme A Dehydrogenase
catalog :
MBS144002
quantity :
1 mg
price :
2220 USD
more info or order :
product information
catalog number :
MBS144002
products type :
Recombinant Protein
products full name :
Recombinant Human Hydroxyacyl-Coenzyme A Dehydrogenase
products short name :
Hydroxyacyl-Coenzyme A Dehydrogenase
products name syn :
HADH Human; Hydroxyacyl-Coenzyme A Dehydrogenase Human Recombinant; EC 1.1.1.35; HAD; HADH1; HHF4; MSCHAD; SCHAD; Hydroxyacyl-coenzyme A dehydrogenase; HCDH; Short-chain 3-hydroxyacyl-CoA dehydrogenase; Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase; HADH; HADHSC; MGC8392
other names :
hydroxyacyl-coenzyme A dehydrogenase, mitochondrial isoform 1; Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial; hydroxyacyl-coenzyme A dehydrogenase, mitochondrial; L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain; medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase; short-chain 3-hydroxyacyl-CoA dehydrogenase; hydroxyacyl-CoA dehydrogenase; Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase; Short-chain 3-hydroxyacyl-CoA dehydrogenase
products gene name :
HADH
other gene names :
HADH; HADH; HAD; HCDH; HHF4; HADH1; SCHAD; HADHSC; MSCHAD; HAD; HADHSC; SCHAD; HCDH
uniprot entry name :
HCDH_HUMAN
host :
E Coli
sequence length :
331
sequence :
MGSSHHHHHH SSGLVPRGSH MSSSSTASAS AKKIIVKHVT VIGGGLMGAG IAQVAAATGH TVVLVDQTED ILAKSKKGIE ESLRKVAKKK FAENPKAGDE FVEKTLSTIA TSTDAASVVH STDLVVEAIV ENLKVKNELF KRLDKFAAEH TIFASNTSSL QITSIANATT RQDRFAGLHF FNPVPVMKLV EVIKTPMTSQ KTFESLVDFS KALGKHPVSC KDTPGFIVNR LLVPYLMEAI RLYERGDASK EDIDTAMKLG AGYPMGPFEL LDYVGLDTTK FIVDGWHEMD AENPLHQPSP SLNKLVAENK FGKKTGEGFY KYK.
purity :
Greater than 95% as determined by SDS-PAGE.
form :
The HADH solution contains 20mM Tris-HCl pH-8, 0.1M NaCl and 20% glycerol. Sterile Filtered clear colorless solution.
products categories :
ENZYMES; Enzymes; Dehydrogenase
products description :
Description: HADH Human Recombinant fused to 21 amino acid His Tag at N-terminal produced in E Coli is a single, non-glycosylated, polypeptide chain containing 323 amino acids (13-314 a.a.) and having a molecular mass of 35.1 kDa. The HADH is purified by proprietary chromatographic techniques. Introduction: HADH is part of the 3-hydroxyacyl-CoA dehydrogenase enzyme family. HADH is involved in mitochondrial matrix to catalyze the oxidation of straight-chain 3-hydroxyacyl-CoAs as part of the beta-oxidation pathway. HADH enzymatic activity is at its peak with medium-chain-length fatty acids. Mutations in HADH cause familial hyperinsulinemic hypoglycemia. HADH participates in fatty acid oxidation, where some enzymes work in a step-wise fashion to break metabolize fats and convert them to energy.
ncbi gi num :
296179427
ncbi acc num :
NP_001171634.2
ncbi gb acc num :
NM_001184705.2
uniprot acc num :
Q16836
ncbi mol weight :
36,051 Da
ncbi pathways :
Beta Oxidation Of Butanoyl-CoA To Acetyl-CoA Pathway 106130!!Beta Oxidation Of Decanoyl-CoA To Octanoyl-CoA-CoA Pathway 106127!!Beta Oxidation Of Hexanoyl-CoA To Butanoyl-CoA Pathway 106129!!Beta Oxidation Of Lauroyl-CoA To Decanoyl-CoA-CoA Pathway 106126!!Beta Oxidation Of Octanoyl-CoA To Hexanoyl-CoA Pathway 106128!!Butanoate Metabolism Pathway 83007!!Butanoate Metabolism Pathway 391!!FOXA2 And FOXA3 Transcription Factor Networks Pathway 137911!!Fatty Acid Beta Oxidation Pathway 198865!!Fatty Acid Biosynthesis Pathway 198873
ncbi summary :
This gene is a member of the 3-hydroxyacyl-CoA dehydrogenase gene family. The encoded protein functions in the mitochondrial matrix to catalyze the oxidation of straight-chain 3-hydroxyacyl-CoAs as part of the beta-oxidation pathway. Its enzymatic activity is highest with medium-chain-length fatty acids. Mutations in this gene cause one form of familial hyperinsulinemic hypoglycemia. The human genome contains a related pseudogene of this gene on chromosome 15. [provided by RefSeq, May 2010]
size :
1 mg
price :
2220 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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