protein

Recombinant Human High-Mobility Group Nucleosome Binding Domain 1

MBS143999

0.01 mg

205 USD

Recombinant Protein

Recombinant Human High-Mobility Group Nucleosome Binding Domain 1

High-Mobility Group Nucleosome Binding Domain 1

HMGN1 Human; High-Mobility Group Nucleosome Binding Domain 1 Human Recombinant; HMG14; GC104230; High-Mobility Group Nucleosome Binding Domain 1

non-histone chromosomal protein HMG-14; Non-histone chromosomal protein HMG-14; non-histone chromosomal protein HMG-14; high mobility group nucleosome-binding domain-containing protein 1; high-mobility group (nonhistone chromosomal) protein 14; high-mobility group nucleosome binding 1; high-mobility group nucleosome binding domain 1; nonhistone chromosomal protein HMG-14; high mobility group nucleosome binding domain 1; High mobility group nucleosome-binding domain-containing protein 1

HMGN1

HMGN1; HMGN1; HMG14; HMG14

HMGN1_HUMAN

E Coli

100

Greater than 95% as determined by SDS-PAGE.

HMGN1 protein solution (0.5mg/ml) containing 20mM Tris-HCl pH-8, 1mM DTT, 0.1M NaCl, 0.1mM PMSF & 20% glycerol. Sterile filtered colorless solution.

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; High-Mobility Group

Description: HMGN1 Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 108 amino acids (1-100 a.a.) and having a molecular mass of 11.7 kDa. HMGN1 protein is fused to an 8 amino acid His-Tag at C-terminus and purified by standard chromatography. Introduction: HMGN1 binds to the inner side of the nucleosomal DNA therefore changing the interaction between the DNA and the histone octamer. HMGN1 participates in the development which maintains transcribable genes in an exceptional chromatin conformation. HMGN1 inhibits the phosphorylation of nucleosomal histones H3 and H2A by RPS6KA5/MSK1 and RPS6KA3/RSK2.

48255933

NP_004956.5

NM_004965.6

P05114

10,659 Da

Herpes Simplex Infection Pathway 377873!!Herpes Simplex Infection Pathway 377865!!P38 MAPK Signaling Pathway 198893

The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMG17, the encoded protein may help maintain an open chromatin configuration around transcribable genes. [provided by RefSeq, Aug 2011]

0.01 mg

205 USD