protein

Recombinant Human Granulysin

MBS143996

0.002 mg

140 USD

Recombinant Protein

Recombinant Human Granulysin

Granulysin

GNLY Human; Granulysin Human Recombinant; LAG2; Lymphokine LAG-2; TLA519; NKG5; LAG2; D2S69E; Granulysin; T-cell activation protein 519; GNLY; D2S69E

granulysin isoform 2; Granulysin; granulysin; T-cell activation protein 519; T-lymphocyte activation gene 519; lymphocyte-activation gene 2; lymphokine LAG-2; granulysin; Lymphokine LAG-2; Protein NKG5; T-cell activation protein 519

GNLY

GNLY; GNLY; 519; LAG2; NKG5; LAG-2; D2S69E; TLA519; LAG2; NKG5; TLA519

GNLY_HUMAN

E Coli

145

Greater than 95.0% as determined by SDS-PAGE.

The Granulysin protein was lyophilized from a concentrated (1mg/ml) solution containing no additives. Sterile Filtered White lyophilized (freeze-dried) powder.

Lyophilized Granulysin although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution Granulysin should be stored at 4 degree C between 2-7 days and for future use below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Solubility: It is recommended to reconstitute the lyophilized Granulysin in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins

Description: GNLY Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 159 amino acids and fused to a double His Tag (N+C terminus) and having a total molecular mass of 18.1 kDa.The GNLY is purified by proprietary chromatographic techniques. Introduction: GNLY is part of the SAPLIP family and is located in the cytotoxic granules of T cells, which are discharged upon antigen stimulation. GNLY is localized in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. GNLY is an antimicrobial protein that kills intracellular pathogens. GNLY is active against a wide range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis.

7108344

NP_006424.2

NM_006433.4

P22749

14,853 Da

The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

GNLY: Antimicrobial protein that kills intracellular pathogens. Active against a broad range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 2p11.2. Cellular Component: extracellular space. Biological Process: killing of cells of another organism; defense response to bacterium; cellular defense response; defense response to fungus

0.002 mg

140 USD

0.01 mg

205

1 mg

3965