product summary
Loading...
company name :
MyBioSource
product type :
protein
product name :
Recombinant Porcine CD163
catalog :
MBS143958
quantity :
0.01 mg
price :
140 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS143958
products type :
Recombinant Protein
products full name :
Recombinant Porcine CD163
products short name :
CD163
products name syn :
CD163 Porcine; CD163 Porcine Recombinant; CD-163; Hemoglobin scavenger receptor; macrophage-associated antigen; M130; sCD163; CD163; MM130
other names :
scavenger receptor cysteine-rich type 1 protein M130; Scavenger receptor cysteine-rich type 1 protein M130; scavenger receptor cysteine-rich type 1 protein M130; CD_antigen: CD163Soluble CD163; sCD163
products gene name :
pCD163
other gene names :
CD163; CD163; M130; sCD163
uniprot entry name :
C163A_PIG
host :
E Coli
sequence length :
1110
purity :
Greater than 95.0% as determined by: (a) Analysis by HPLC. (b) Analysis by SDS-PAGE.
form :
The protein was lyophilized from a 0.2 um filtered concentrated solution in 1xPBS, pH 7.4, containing 4M Urea. Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
Lyophilized CD163 although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution CD163 should be stored at 4 degree C between 2-7 days and for future use below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
other info2 :
Solubility: It is recommended to reconstitute the lyophilized CD163 in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
products categories :
RECOMBINANT & NATURAL PROTEINS; CD Antigens
products description :
Description: CD163 Porcine Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 805 amino acids and having a molecular mass of 87kDa.The CD163 is fused to an 8 amino acid His Tag at C-terminus and purified by proprietary chromatographic techniques. Introduction: CD163 is an acute phase-regulated receptor which participates in the removal and endocytosis of hemoglobin/haptoglobin complexes by macrophages and thus keeps tissues from free hemoglobin-mediated oxidative damage. Furthermore, CD163 partakes in the uptake and recycling of iron, through endocytosis of hemoglobin/haptoglobin and ensuing breakdown of heme. In addition, CD163 binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent way. CD163 demonstrates greater affinity for complexes of hemoglobin and multimeric haptoglobin of HP-1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP-1S phenotype. Moreover, CD163 stimulates a cascade of intracellular signals which involves tyrosine kinase-dependent calcium recruitment, inositol triphosphate formation and secretion of IL-6 & CSF-1.
ncbi gi num :
47522778
ncbi acc num :
NP_999141.1
ncbi gb acc num :
NM_213976.1
uniprot acc num :
Q2VL90
ncbi mol weight :
94,061 Da
size1 :
0.01 mg
price1 :
140 USD
size2 :
0.05 mg
price2 :
205
size3 :
1 mg
price3 :
1790
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!