product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Catenin, Beta Interacting Protein 1
catalog :
MBS143957
quantity :
0.005 mg
price :
140 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS143957
products type :
Recombinant Protein
products full name :
Recombinant Human Catenin, Beta Interacting Protein 1
products short name :
Catenin, Beta Interacting Protein 1
products name syn :
CTNNBIP1 Human; Catenin, Beta Interacting Protein 1 Human Recombinant; ICAT; MGC15093; CNBP1; CTNNBIP1; Beta-catenin-interacting protein 1; Inhibitor of beta-catenin and Tcf-4
other names :
beta-catenin-interacting protein 1; Beta-catenin-interacting protein 1; beta-catenin-interacting protein 1; beta-catenin-interacting protein ICAT; inhibitor of beta-catenin and Tcf-4; catenin, beta interacting protein 1; Inhibitor of beta-catenin and Tcf-4
products gene name :
CTNNBIP1
other gene names :
CTNNBIP1; CTNNBIP1; ICAT; ICAT
uniprot entry name :
CNBP1_HUMAN
host :
E Coli
sequence length :
81
sequence :
MGSSHHHHHH SSGLVPRGSH MNREGAPGKS PEEMYIQQKV RVLLMLRKMG SNLTASEEEF LRTYAGVVNS QLSQLPPHSI DQGAEDVVMA FSRSETEDRR Q.
purity :
Greater than 90.0% as determined by SDS-PAGE.
form :
CTNNBIP1 Human solution containing 20mM Tris HCL pH-7.5, 2mM DTT, 0.1M NaCl & 20% glycerol. Sterile filtered colorless solution.
storage stability :
CTNNBIP1 Human although stable at 4 degree C for 1 week, should be stored desiccated below -18 degree C. Please prevent freeze thaw cycles.
products categories :
RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins
products description :
Description: CTNNBIP1 Recombinant E Coli produced in E Coli is a single, non-glycosylated polypeptide chain containing 101 amino acids (1-81 a.a.) and having a molecular mass of 11.3 kDa. The CTNNBIP1 is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. Introduction: CTNNBIP1 binds CTNNB1 and avoids interaction between CTNNB1 and TCF (T-cell transcription factor) family members. CTNNBIP1 is a negative regulator of the Wnt signaling pathway.
ncbi gi num :
59889555
ncbi acc num :
NP_001012329.1
ncbi gb acc num :
NM_001012329.1
uniprot acc num :
Q9NSA3
ncbi mol weight :
9,170 Da
ncbi pathways :
Disease Pathway (530764); RNF Mutants Show Enhanced WNT Signaling And Proliferation Pathway (1127632); Regulation Of Wnt-mediated Beta Catenin Signaling And Target Gene Transcription Pathway (169352); Signal Transduction Pathway (477114); Signaling By WNT In Cancer Pathway (1127614); Signaling By Wnt Pathway (106510); TCF Dependent Signaling In Response To WNT Pathway (1127516); Wnt Signaling Pathway NetPath (198799); Wnt Signaling Pathway (83061); Wnt Signaling Pathway (471)
ncbi summary :
The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. The encoded protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
CTNNBIP1: Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt signaling pathway. Belongs to the CTNNBIP1 family. Protein type: Cell development/differentiation; Inhibitor. Chromosomal Location of Human Ortholog: 1p36.22. Cellular Component: nucleoplasm; cytoplasm; nucleus; beta-catenin destruction complex; cytosol. Molecular Function: protein binding; beta-catenin binding. Biological Process: anterior/posterior pattern formation; positive regulation of monocyte differentiation; positive regulation of osteoblast differentiation; Wnt receptor signaling pathway; negative regulation of Wnt receptor signaling pathway; ureteric bud branching; negative regulation of smooth muscle cell proliferation; negative regulation of transcription factor activity; negative regulation of protein binding; regulation of vascular permeability during acute inflammatory response; negative regulation of DNA binding
size1 :
0.005 mg
price1 :
140 USD
size2 :
0.025 mg
price2 :
205
size3 :
1 mg
price3 :
2220
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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