product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Adenosylhomocysteinase
catalog :
MBS143940
quantity :
0.02 mg
price :
205 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS143940
products type :
Recombinant Protein
products full name :
Recombinant Human Adenosylhomocysteinase
products short name :
Adenosylhomocysteinase
products name syn :
AHCY Human; Adenosylhomocysteinase Human Recombinant; EC 3.3.1.1; SAHH; AdoHcyase; S-adenosyl-L-homocysteine hydrolase; Adenosylhomocysteinase
other names :
adenosylhomocysteinase isoform 1; Adenosylhomocysteinase; adenosylhomocysteinase; S-adenosyl-L-homocysteine hydrolase; S-adenosylhomocysteine hydrolase; adenosylhomocysteinase; S-adenosyl-L-homocysteine hydrolase
products gene name :
AHCY
other gene names :
AHCY; AHCY; SAHH; adoHcyase; SAHH; AdoHcyase
uniprot entry name :
SAHH_HUMAN
host :
E Coli
sequence length :
432
sequence :
MGSSHHHHHH SSGLVPRGSH MSDKLPYKVA DIGLAAWGRK ALDIAENEMP GLMRMRERYS ASKPLKGARI AGCLHMTVET AVLIETLVTL GAEVQWSSCN IFSTQDHAAA AIAKAGIPVY AWKGETDEEY LWCIEQTLYF KDGPLNMILD DGGDLTNLIH TKYPQLLPGI RGISEETTTG VHNLYKMMAN GILKVPAINV NDSVTKSKFD NLYGCRESLI DGIKRATDVM IAGKVAVVAG YGDVGKGCAQ ALRGFGARVI ITEIDPINAL QAAMEGYEVT TMDEACQEGN IFVTTTGCID IILGRHFEQM KDDAIVCNIG HFDVEIDVKW LNENAVEKVN IKPQVDRYRL KNGRRIILLA EGRLVNLGCA MGHPSFVMSN SFTNQVMAQI ELWTHPDKYP VGVHFLPKKL DEAVAEAHLG KLNVKLTKLT EKQAQYLGMS CDGPFKPDHY RY.
purity :
Greater than 95.0% as determined by SDS-PAGE.
form :
AHCY Human solution containing 20mM Trsi pH-8, & 10% glycerol. Sterile filtered colorless solution.
storage stability :
AHCY Human although stable at 4 degree C for 1 week, should be stored desiccated below -18 degree C. Please prevent freeze thaw cycles.
products categories :
ENZYMES; Enzymes
products description :
Description: AHCY Recombinant Human produced in E Coli is a single, non-glycosylated polypeptide chain containing 452 amino acids (1-432 a.a.) and having a molecular mass of 49.8 kDa. The AHCY is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. Introduction: AHCY is an enzyme that catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). AHCY controls the intracellular S-adenosylhomocysteine (SAH) concentration that is crucial for transmethylation reactions. AHCY deficiency causes hypermethioninemia.
ncbi gi num :
9951915
ncbi acc num :
NP_000678.1
ncbi gb acc num :
NM_000687.2
uniprot acc num :
P23526
ncbi mol weight :
44,659 Da
ncbi pathways :
Biological Oxidations Pathway 105698!!Cysteine And Methionine Metabolism Pathway 104488!!Cysteine And Methionine Metabolism Pathway 103421!!Defective AHCY Causes Hypermethioninemia With S-adenosylhomocysteine Hydrolase Deficiency (HMAHCHD) Pathway 1127639!!Defective GCLC Causes Hemolytic Anemia Due To Gamma-glutamylcysteine Synthetase Deficiency (HAGGSD) Pathway 1127658!!Defective GGT1 Causes Glutathionuria (GLUTH) Pathway 1127659!!Defective GSS Causes Glutathione Synthetase Deficiency (GSS Deficiency) Pathway 1127660!!Defective MAT1A Causes Methionine Adenosyltransferase Deficiency (MATD) Pathway 1127663!!Defective OPLAH Causes 5-oxoprolinase Deficiency (OPLAHD) Pathway 1127661!!Defective SLC35D1 Causes Schneckenbecken Dysplasia (SCHBCKD) Pathway 1127665
ncbi summary :
S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]
size :
0.02 mg
price :
205 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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