protein

Recombinant Human Adenosine Kinase

MBS143939

0.01 mg

205 USD

Recombinant Protein

Recombinant Human Adenosine Kinase

Adenosine Kinase

ADK Human; Adenosine Kinase Human Recombinant; Adenosine 5''-phosphotransferase; EC 2.7.1.20; AK; ADK

adenosine kinase isoform a; Adenosine kinase; adenosine kinase; adenosine 5'-phosphotransferase; adenosine kinase; Adenosine 5'-phosphotransferase

ADK

ADK; ADK; AK; AK

ADK_HUMAN

E Coli

345

MGSSHHHHHH SSGLVPRGSH MRENILFGMG NPLLDISAVV DKDFLDKYSL KPNDQILAED KHKELFDELV KKFKVEYHAG GSTQNSIKVA QWMIQQPHKA ATFFGCIGID KFGEILKRKA AEAHVDAHYY EQNEQPTGTC AACITGDNRS LIANLAAANC YKKEKHLDLE KNWMLVEKAR VCYIAGFFLT VSPESVLKVA HHASENNRIF TLNLSAPFIS QFYKESLMKV MPYVDILFGN ETEAATFARE QGFETKDIKE IAKKTQALPK MNSKRQRIVI FTQGRDDTIM ATESEVTAFA VLDQDQKEII DTNGAGDAFV GGFLSQLVSD KPLTECIRAG HYAASIIIRR TGCTFPEKPD FH.

Greater than 95% as determined by SDS-PAGE.

ADK Human solution containing 20mM Trsi HCL pH-8, 1mM DTT, 1mM EDTA, 50mM NaCl & 20% glycerol. Sterile filtered colorless solution.

Adenosine Kinase Human although stable at 4 degree C for 1 week, should be stored desiccated below -18 degree C. Please prevent freeze thaw cycles.

PROTEIN KINASES; Enzymes; Adenylate Kinase

Description: Adenosine Kinase Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 362 amino acids (22-362a.a.) and having a molecular mass of 40.5 kDa. Adenosine Kinase protein is fused to a 21 amino acid His tag at N-terminus and is purified by standard chromatography. Introduction: Adenosine Kinase is an abundant enzyme in mammalian tissues which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thus is as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has extensive effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme take a crucial pharmacological part in growing intravascular adenosine concentrations and acting as anti-inflammatory agents.

32484973

NP_001114.2

NM_001123.3

P55263

36,580 Da

Metabolic Pathways 132956!!Metabolism Pathway 477135!!Metabolism Of Nucleotides Pathway 106263!!Purine Metabolism Pathway 82944!!Purine Metabolism Pathway 106265!!Purine Metabolism Pathway 307!!Purine Salvage Pathway 106273!!Adenine And Adenosine Salvage II Pathway 547496!!Adenine And Adenosine Salvage II Pathway 545491!!Superpathway Of Purine Nucleotide Salvage 907942

This gene an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]

0.01 mg

205 USD