Recombinant Human Aldehyde Dehydrogenase 1A1 | MyBioSource MBS143915 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Human Aldehyde Dehydrogenase 1A1

catalog :

MBS143915

quantity :

0.02 mg

price :

205 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS143915

products type :

Recombinant Protein

products full name :

Recombinant Human Aldehyde Dehydrogenase 1A1

products short name :

Aldehyde Dehydrogenase 1A1

products name syn :

ALDH1A1 Human; Aldehyde Dehydrogenase 1A1 Human Recombinant; ALDC; Aldehyde dehydrogenase cytosolic; Aldehyde dehydrogenase family 1 member A1; ALDH1; ALDH11; ALDH-E1; ALHDII; MGC2318; PUMB1; RalDH1; RALDH1; RALDH 1; Retinal dehydrogenase 1; ALDH1A1

other names :

retinal dehydrogenase 1; Retinal dehydrogenase 1; retinal dehydrogenase 1; ALDH class 1; ALHDII; RALDH 1; acetaldehyde dehydrogenase 1; aldehyde dehydrogenase 1, soluble; aldehyde dehydrogenase, liver cytosolic; epididymis luminal protein 12; epididymis luminal protein 9; epididymis secretory sperm binding protein Li 53e; retinaldehyde dehydrogenase 1; aldehyde dehydrogenase 1 family, member A1; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolic

products gene name :

ALDH1A1

other gene names :

ALDH1A1; ALDH1A1; ALDC; ALDH1; HEL-9; HEL12; PUMB1; ALDH11; RALDH1; ALDH-E1; HEL-S-53e; ALDC; ALDH1; PUMB1; RALDH 1; RalDH1

uniprot entry name :

AL1A1_HUMAN

host :

E Coli

sequence length :

501

sequence :

MSSSGTPDLP VLLTDLKIQY TKIFINNEWH DSVSGKKFPV FNPATEEELC QVEEGDKEDV DKAVKAARQA FQIGSPWRTM DASERGRLLYKLADLIERDR LLLATMESMN GGKLYSNAYL NDLAGCIKTL RYCAGWADKI QGRTIPIDGN FFTYTRHEPI GVCGQIIPWN FPLVMLIWKIGPALSCGNTV VVKPAEQTPL TALHVASLIK EAGFPPGVVN IVPGYGPTAG AAISSHMDID KVAFTGSTEV GKLIKEAAGK SNLKRVTLEL GGKSPCIVLA DADLDNAVEF AHHGVFYHQG QCCIAASRIF VEESIYDEFV RRSVERAKKY ILGNPLTPGV TQGPQIDKEQ YDKILDLIES GKKEGAKLEC GGGPWGNKGY FVQPTVFSNV TDEMRIAKEE IFGPVQQIMK FKSLDDVIKR ANNTFYGLSA GVFTKDIDKA ITISSALQAG TVWVNCYGVV SAQCPFGGFK MSGNGRELGE YGFHEYTEVK TVTVKISQKN S.

purity :

Greater than 90% as determined by SDS-PAGE.

form :

The ALDH1A1 protein solution is formulated in 50mM Tris-HCl pH-7.5 and 10% glycerol. Sterile Filtered clear solution.

storage stability :

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time.Please avoid freeze thaw cycles.

products categories :

ENZYMES; Enzymes; Dehydrogenase

products description :

Description: The ALDH1A1 Human recombinant protein is a single, non-glycosilated polypeptide chain produced in E Coli, having a molecular weight of 54.8kDa and containing 501 amino acids (1-501 a.a.). Introduction: ALDH1A1 is part of the aldehyde dehydrogenases family. Aldehyde dehydrogenase is the 2nd protein of the main oxidative pathway of alcohol metabolism. Cytosolic and mitochondrial are 2 main liver isoforms of ALDH that are differentiateed by their electrophoretic mobility, kinetic property, & subcellular localization. The majority of Caucasians have two main isozymes, whereas just about 50% of Orientals have only the cytosolic form, excluding the mitochondrial form. ALDH1A1 is also a member of the group of corneal crystallins that assist the transparency of the cornea. (Retinal + NAD+ + H2O = retinoate + NADH).

ncbi gi num :

21361176

ncbi acc num :

NP_000680.2

ncbi gb acc num :

NM_000689.4

uniprot acc num :

P00352

ncbi mol weight :

54,862 Da

ncbi pathways :

Biological Oxidations Pathway 105698!!Defective CYP11A1 Causes Adrenal Insufficiency, Congenital, With 46,XY Sex Reversal (AICSR) Pathway 1127640!!Defective CYP11B1 Causes Adrenal Hyperplasia 4 (AH4) Pathway 1127641!!Defective CYP11B2 Causes Corticosterone Methyloxidase 1 Deficiency (CMO-1 Deficiency) Pathway 1127642!!Defective CYP17A1 Causes Adrenal Hyperplasia 5 (AH5) Pathway 1127643!!Defective CYP19A1 Causes Aromatase Excess Syndrome (AEXS) Pathway 1127644!!Defective CYP1B1 Causes Glaucoma Pathway 1127645!!Defective CYP21A2 Causes Adrenal Hyperplasia 3 (AH3) Pathway 1127646!!Defective CYP24A1 Causes Hypercalcemia, Infantile (HCAI) Pathway 1127647!!Defective CYP26B1 Causes Radiohumeral Fusions With Other Skeletal And Craniofacial Anomalies (RHFCA) Pathway 1127648

ncbi summary :

The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet. [provided by RefSeq, Mar 2011]

size :

0.02 mg

price :

205 USD

more info or order :

MyBioSource product webpage