product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human B-Cell Lymphoma Protein 2 Alpha, His Tag
catalog :
MBS143903
quantity :
0.02 mg
price :
205 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS143903
products type :
Recombinant Protein
products full name :
Recombinant Human B-Cell Lymphoma Protein 2 Alpha, His Tag
products short name :
B-Cell Lymphoma Protein 2 Alpha
products name syn :
BCL2 Human, His; B-Cell Lymphoma Protein 2 Alpha Human Recombinant, His Tag; Apoptosis regulator Bcl-2; BCL2; B-cell CLL/lymphoma 2; Bcl-2; BCL2 His
other names :
apoptosis regulator Bcl-2 alpha isoform; Apoptosis regulator Bcl-2; apoptosis regulator Bcl-2; protein phosphatase 1, regulatory subunit 50; B-cell CLL/lymphoma 2
products gene name :
BCL2
other gene names :
BCL2; BCL2; Bcl-2; PPP1R50
uniprot entry name :
BCL2_HUMAN
host :
E Coli
sequence length :
239
purity :
Greater than 90.0% as determined by SDS-PAGE.
form :
The BCL2 protein solution contains 20mM Tris-HCl, pH-8, 2mM DTT and 20% glycerol. Sterile filtered colorless solution.
storage stability :
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
products categories :
RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; B Cell Lymphoma
products description :
Description: BCL2 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing amino acids 1-211 and having a molecular mass of 25.4 kDa. The BCL2 is fused to a 20 a.a. His-Tag at N-terminus and purified by proprietary chromatographic techniques. Introduction: BCL2 gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.
ncbi gi num :
72198189
ncbi acc num :
NP_000624.2
ncbi gb acc num :
NM_000633.2
uniprot acc num :
P10415
ncbi mol weight :
22,337 Da
ncbi pathways :
ATF-2 Transcription Factor Network Pathway 138006!!Activation Of BAD And Translocation To Mitochondria Pathway 105659!!Activation Of BH3-only Proteins Pathway 105658!!Adrenergic Signaling In Cardiomyocytes Pathway 908257!!Adrenergic Signaling In Cardiomyocytes Pathway 909696!!Amyotrophic Lateral Sclerosis (ALS) Pathway 920975!!Amyotrophic Lateral Sclerosis (ALS) Pathway 83099!!Amyotrophic Lateral Sclerosis (ALS) Pathway 511!!Apoptosis Pathway 198797!!Apoptosis Pathway 83060
ncbi summary :
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq, Jul 2008]
size :
0.02 mg
price :
205 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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