catalog number :
MBS143845
products type :
Recombinant Protein
products full name :
Recombinant Human Cytokeratin 18 His Tag
products short name :
Cytokeratin 18
products name syn :
KRT18 Human, His; Cytokeratin 18 Human Recombinant, His Tag; Keratin type I cytoskeletal 18; Cytokeratin-18; CK-18; Keratin-18; K18; KRT18; CYK18; Cell proliferation-inducing gene 46 protein; KRT18 His
other names :
keratin, type I cytoskeletal 18; Keratin, type I cytoskeletal 18; keratin, type I cytoskeletal 18; CK-18; cell proliferation-inducing gene 46 protein; cell proliferation-inducing protein 46; cytokeratin 18; cytokeratin-18; keratin 18, type I; Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18; Keratin-18; K18
products gene name :
KRT18
other gene names :
KRT18; KRT18; K18; CYK18; CYK18; CK-18; K18
uniprot entry name :
K1C18_HUMAN
purity :
Greater than 95.0% as determined by SDS-PAGE.
form :
The KRT18 protein solution (0.8mg/ml) contains 20mM Tris pH 8, 5mM EDTA and 50% glycerol. Sterile Filtered colorless solution.
storage stability :
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. Please avoid freeze thaw cycles.
products categories :
RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; Cytokeratin
products description :
Description: KRT18 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain having a calculated molecular mass of 52.42kDa.The KRT18 is fused to a His Tag at N-terminus and purified by proprietary chromatographic techniques. Introduction: KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.
ncbi acc num :
NP_000215.1
ncbi gb acc num :
NM_000224.2
ncbi mol weight :
48,058 Da
ncbi pathways :
Caspase Cascade In Apoptosis Pathway 137974!!EGFR1 Signaling Pathway 198782!!Pathogenic Escherichia Coli Infection Pathway 83103!!Pathogenic Escherichia Coli Infection Pathway 672459!!Pathogenic Escherichia Coli Infection Pathway 516
ncbi summary :
KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]