protein

Recombinant Human Fructose-1,6-Bisphosphatase 1

MBS143831

1 mg

2220 USD

Recombinant Protein

Recombinant Human Fructose-1,6-Bisphosphatase 1

Fructose-1,6-Bisphosphatase 1

FBP1 Human; Fructose-1,6-Bisphosphatase 1 Human Recombinant; FBP1; FBP; D-fructose-1; 6-bisphosphate 1-phosphohydrolase 1; FBPase 1; Fructose-1; 6-bisphosphatase 1

fructose-1,6-bisphosphatase 1; Fructose-1,6-bisphosphatase 1; fructose-1,6-bisphosphatase 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase 1; FBPase 1; fructose-bisphosphatase 1; growth-inhibiting protein 17; liver FBPase; fructose-1,6-bisphosphatase 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase 1; Liver FBPase

FBP1

FBP1; FBP1; FBP; FBP; FBPase 1

F16P1_HUMAN

E Coli

338

MGSSHHHHHH SSGLVPRGSH MADQAPFDTD VNTLTRFVME EGRKARGTGE LTQLLNSLCT AVKAISSAVR KAGIAHLYGI AGSTNVTGDQ VKKLDVLSND LVMNMLKSSF ATCVLVSEED KHAIIVEPEK RGKYVVCFDP LDGSSNIDCL VSVGTIFGIY RKKSTDEPSE KDALQPGRNL VAAGYALYGS ATMLVLAMDC GVNCFMLDPA IGEFILVDKD VKIKKKGKIY SLNEGYARDF DPAVTEYIQR KKFPPDNSAP YGARYVGSMV ADVHRTLVYG GIFLYPANKK SPNGKLRLLY ECNPMAYVME KAGGMATTGK EAVLDVIPTD IHQRAPVILG SPDDVLEFLK VYEKHSAQ.

Greater than 90% as determined by SDS-PAGE.

The FBP1 protein solution is formulated in 20mM Tris-HCl pH-8, 1mM DTT and 10% glycerol. Sterile Filtered clear solution.

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time.Please avoid freeze thaw cycles.

ENZYMES; Enzymes; Phosphatase

Description: The FBP1 Human recombinant protein is a single, non-glycosilated polypeptide chain produced in E Coli, having a molecular weight of 39kDa and containing 358 amino acids (1-338 a.a.). The FBP1 enzyme is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatography techniques. Introduction: FBP1 is a gluconeogenesis regulatory protein which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBP1 deficiency is associated with hypoglycemia and metabolic acidosis. FBP1 regulates mouse endogenous glucose production. FBP1 coupled with phosphofructokinase (PFK) takes part in the metabolism of pancreatic islet cells.

16579888

NP_000498.2

NM_000507.3

P09467

36,842 Da

AMPK Signaling Pathway 989139!!AMPK Signaling Pathway 992181!!Carbon Metabolism Pathway 814926!!Carbon Metabolism Pathway 817567!!Disease Pathway 530764!!Fructose And Mannose Metabolism Pathway 82930!!Fructose And Mannose Metabolism Pathway 291!!Gluconeogenesis Pathway 106204!!Gluconeogenesis, Oxaloacetate = Fructose-6P Pathway 413342!!Gluconeogenesis, Oxaloacetate = Fructose-6P Pathway 468196

Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis. [provided by RefSeq, Jul 2008]

1 mg

2220 USD