This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
protein
product name :
Recombinant Human GTP-Binding Protein SAR1A
catalog :
MBS143823
quantity :
0.02 mg
price :
205 USD
product information
catalog number :
MBS143823
products type :
Recombinant Protein
products full name :
Recombinant Human GTP-Binding Protein SAR1A
products short name :
GTP-Binding Protein SAR1A
products name syn :
SAR1A Human; GTP-Binding Protein SAR1A Human Recombinant; GTP-binding protein SAR1a; COPII-associated small GTPase; SAR1A; SAR1; SARA; SARA1
other names :
GTP-binding protein SAR1a; GTP-binding protein SAR1a; GTP-binding protein SAR1a; COPII-associated small GTPase; SAR1 gene homolog A; SAR1 homolog A; SAR1a gene homolog 1; secretion associated, Ras related GTPase 1A; COPII-associated small GTPase
products gene name :
SAR1A
other gene names :
SAR1A; SAR1A; SAR1; Sara; SARA1; masra2; SAR1; SARA; SARA1
uniprot entry name :
SAR1A_HUMAN
host :
E Coli
sequence length :
198
sequence :
MGSSHHHHHH SSGLVPRGSH MSFIFEWIYN GFSSVLQFLG LYKKSGKLVF LGLDNAGKTT LLHMLKDDRL GQHVPTLHPT SEELTIAGMT FTTFDLGGHE QARRVWKNYL PAINGIVFLV DCADHSRLVE SKVELNALMT DETISNVPIL ILGNKIDRTD AISEEKLREI FGLYGQTTGK GNVTLKELNA RPMEVFMCSV LKRQGYGEGF RWLSQYID.
purity :
Greater than 90.0% as determined by SDS-PAGE.
form :
The SAR1A solution contains 20mM Tris-HCl buffer (pH8.0), 1mM DTT and 10% glycerol. Sterile Filtered colorless solution.
storage stability :
SAR1A although stable 4 degree C for 4 weeks, should be stored desiccated below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
products categories :
RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins
products description :
Description: SAR1A Human Recombinant fused with 20 amino acid His tag at N-terminus produced in E Coli is a single, non-glycosylated, polypeptide chain containing 218 amino acids (1- 198 a.a.) and having a molecular mass of 24.5kDa.The SAR1A is purified by proprietary chromatographic techniques. Introduction: SAR1A is a member of the small GTPase superfamily. SAR1A is a vital component of COPII vesicle coats involved in export of cargo from the ER (Endoplasmic Reticulum). The GTPase activity of SAR1A serves as a molecular switch to control protein-protein and protein-lipid interactions which dictate vesicle budding from the ER. SAR1A, while GDP-bound interacts with the membrane-bound exchange factor Sec12 and trades its bound GDP for GTP. SAR1A is also involved in the transport from the ER to the Golgi apparatus. SAR1A is required to maintain SEC16A localization at distinct locations on the ER membrane possibly by preventing its dissociation. SAR1A-GTP-dependent compilation of SEC16A on the ER membrane creates a structured scaffold defining endoplasmic reticulum exit sites.
ncbi gi num :
217416369
ncbi acc num :
NP_001136120.1
ncbi gb acc num :
NM_001142648.1
uniprot acc num :
Q9NR31
ncbi mol weight :
17,500 Da
ncbi pathways :
COPII Complex Pathway 413469!!COPII Complex Pathway 890619!!Legionellosis Pathway 469200!!Legionellosis Pathway 469186!!Protein Processing In Endoplasmic Reticulum Pathway 167325!!Protein Processing In Endoplasmic Reticulum Pathway 167190!!SREBP Signalling Pathway 219802
size :
0.02 mg
price :
205 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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