product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Mouse Interferon-beta
catalog :
MBS143787
quantity :
0.005 mg
price :
140 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS143787
products type :
Recombinant Protein
products full name :
Recombinant Mouse Interferon-beta
products short name :
Interferon-beta
products name syn :
IFN b Mouse, His; Interferon Beta Mouse Recombinant, His Tag; Leukocyte interferon; B cell interferon; Type I interferon; IFNB1; IFB; IFF; IFNB; IFN-b 1b; MGC96956
other names :
interferon beta; Interferon beta; interferon beta; interferon beta 1, fibroblast
products gene name :
mIFNB
other gene names :
Ifnb1; Ifnb1; Ifb; IFNB; IFN-beta; Ifb; Ifnb; IFN-beta
uniprot entry name :
IFNB_MOUSE
host :
E Coli
sequence length :
182
sequence :
MGSSHHHHHH SSGLVPRGSH MINYKQLQLQ ERTNIRKCQE LLEQLNGKIN LTYRADFKIP MEMTEKMQKS YTAFAIQEML QNVFLVFRNN FSSTGWNETI VVRLLDELHQ QTVFLKTVLE EKQEERLTWE MSSTALHLKS YYWRVQRYLK LMKYNSYAWM VVRAEIFRNF LIIRRLTRNF QN.
purity :
Greater than 95% as determined by Analysis by SDS-PAGE.
form :
The IFN-Beta (0.25mg/ml) contains 20mM HEPES (pH6.0), 0.5M NaCl & 10% glycerol. Sterile filtered colorless solution.
storage stability :
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
products categories :
CYTOKINES AND GROWTH FACTORS; Cytokines; Interferon
products description :
Description: Interferon beta Mouse Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 182 amino acids (22-182 a.a.) and having a molecular mass of 22 kDa. Mouse IFN beta is fused to 20 amino acid at N-terminus and purified by proprietary chromatographic techniques. Introduction: Interferon-beta 1b has antiviral, antibacterial and anticancer activities.Influenza A viruses not only inhibit IFN-beta gene induction but also supress Type-I IFN signaling via mechanism involving induction of the SOCS-3 protein.Intracellular bacteria and cytosolic poly (dA-dT) trigger IFN-beta responses in different human cells without requiring human ZBP1.
ncbi gi num :
6754304
ncbi acc num :
NP_034640.1
ncbi gb acc num :
NM_010510.1
uniprot acc num :
P01575
ncbi mol weight :
22,127 Da
ncbi pathways :
Chagas Disease (American Trypanosomiasis) Pathway (147810); Chagas Disease (American Trypanosomiasis) Pathway (147795); Cytokine Signaling In Immune System Pathway (1110778); Cytokine-cytokine Receptor Interaction Pathway (83248); Cytokine-cytokine Receptor Interaction Pathway (460); Cytokines And Inflammatory Response (BioCarta) Pathway (198283); Cytosolic DNA-sensing Pathway (125146); Cytosolic DNA-sensing Pathway (124833); EBV LMP1 Signaling Pathway (198354); Factors Involved In Megakaryocyte Development And Platelet Production Pathway (1110062)
uniprot summary :
IFNB1: Has antiviral, antibacterial and anticancer activities. Belongs to the alpha/beta interferon family. Protein type: Secreted, signal peptide; Secreted. Cellular Component: extracellular space; extracellular region. Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor binding; interferon-alpha/beta receptor binding; cytokine activity. Biological Process: B cell proliferation; adaptive immune response; cytokine and chemokine mediated signaling pathway; regulation of MHC class I biosynthetic process; defense response; negative regulation of T cell differentiation; humoral immune response; T cell activation during immune response; response to exogenous dsRNA; negative regulation of viral genome replication; B cell differentiation; defense response to bacterium; natural killer cell activation during immune response; innate immune response; positive regulation of transcription from RNA polymerase II promoter; defense response to virus; B cell activation during immune response; positive regulation of peptidyl-serine phosphorylation of STAT protein
size1 :
0.005 mg
price1 :
140 USD
size2 :
0.025 mg
price2 :
205
size3 :
1 mg
price3 :
2665
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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