Recombinant Human Fatty Acid Binding Protein-2, His Tag | MyBioSource MBS143779 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Human Fatty Acid Binding Protein-2, His Tag

catalog :

MBS143779

quantity :

0.005 mg

price :

140 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS143779

products type :

Recombinant Protein

products full name :

Recombinant Human Fatty Acid Binding Protein-2, His Tag

products short name :

Fatty Acid Binding Protein-2

products name syn :

FABP2 Human, His; Fatty Acid Binding Protein 2 Human Recombinant, His Tag; Fatty acid-binding protein 2; IFABP; I-FABP; FABPI; FABP-2; Fatty acid-binding protein intestinal; FABP2; MGC133132; FABP2 His

other names :

fatty acid-binding protein, intestinal; Fatty acid-binding protein, intestinal; fatty acid-binding protein, intestinal; fatty acid-binding protein 2; intestinal-type fatty acid-binding protein; fatty acid binding protein 2, intestinal; Fatty acid-binding protein 2; Intestinal-type fatty acid-binding protein; I-FABP

products gene name :

FABP2

other gene names :

FABP2; FABP2; FABPI; I-FABP; FABPI; I-FABP

uniprot entry name :

FABPI_HUMAN

host :

E Coli

sequence length :

132

purity :

Greater than 95% as determined by SDS-PAGE.

form :

FABP2 His-Tag is supplied in 20mM Tris-HCl pH 8 and 10% glycerol. Sterile Filtered colorless liquid formulation.

concentration :

25ug/25ul

storage stability :

Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time.Please avoid freeze thaw cycles.

products categories :

RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins; FABP

products description :

Description: FABP2 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 132 amino acids and having a molecular mass of 17.3kDa. FABP2 is fused to a 20 aa His tag at N-terminus and purified by standard chromatography techniques. Introduction: FABP multigene family has almost 20 known members. FABPs are divided into 3 different types: hepatic, intestinal and cardiac which form 14-15 kDa proteins that take part in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. FABPs are involved in the modulation of cell growth and proliferation. Intestinal FABP (FABP2) gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance. High serum levels of FABP2 is ulcerative colitis indicates ileitis. FABP2 is has part in triglyceride-rich lipoprotein synthesis. FABP2 binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long- chain fatty acids. FABP2 helps maintain energy homeostasis by functioning as a lipid sensor.

ncbi gi num :

194097325

ncbi acc num :

NP_000125.2

ncbi gb acc num :

NM_000134.3

uniprot acc num :

P12104

ncbi mol weight :

15,207 Da

ncbi pathways :

Fat Digestion And Absorption Pathway (194385); Fat Digestion And Absorption Pathway (194324); PPAR Signaling Pathway (83042); PPAR Signaling Pathway (450)

ncbi summary :

The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance. [provided by RefSeq, Jul 2008]

uniprot summary :

FABP2: FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long- chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. Chromosomal Location of Human Ortholog: 4q28-q31. Cellular Component: cytoplasm. Molecular Function: transporter activity; fatty acid binding. Biological Process: transport; digestion

size1 :

0.005 mg

price1 :

140 USD

size2 :

0.025 mg

price2 :

205

size3 :

1 mg

price3 :

2460

more info or order :

MyBioSource product webpage