catalog number :
MBS143764
products type :
Recombinant Protein
products full name :
Recombinant Human Brain and Acute Leukemia, Cytoplasmatic
products short name :
Acute Leukemia, Cytoplasmatic
products name syn :
BAALC Human; Brain and Acute Leukemia Cytoplasmatic Human Recombinant; Brain and acute leukemia cytoplasmic protein; FLJ12015; BAALC
other names :
brain and acute leukemia cytoplasmic protein isoform 2; Brain and acute leukemia cytoplasmic protein; brain and acute leukemia cytoplasmic protein; brain and acute leukemia, cytoplasmic
products gene name :
BAALC
other gene names :
BAALC; BAALC
uniprot entry name :
BAALC_HUMAN
sequence :
MGSSHHHHHH SSGLVPRGSH MGCGGSRADA IEPRYYESWT RETESTWLTY TDSDAPPSAA APDSGPEAGG LHSGMLEDGL PSNGVPRSTA PGGIPNPEKK TNCETQCPNP QSLSSGPLTQ KQNGLQTTEA KRDAKRMPAK EVTINVTDSI QQMDRSRRIT KNCVN.
purity :
Greater than 95.0% as determined by SDS-PAGE.
form :
The protein solution contains 20mM Tris buffer pH-8, 1mM DTT, 20% glycerol and 2mM EDTA. Sterile filtered colorless solution.
storage stability :
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
products categories :
RECOMBINANT & NATURAL PROTEINS; Recombinant Proteins
products description :
Description: BAALC Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 165 amino acids (1-145 a.a.) and having a molecular mass of 17.7 kDa. The BAALC protein is fused to a 20 amino acid His Tag at N-terminus and purified by standard chromatogrpahy techniques. Introduction: BAALC gene is found in patients with acute myeloid leukemia and is conserved among mammals and is not found in lower organisms. Tissues which express BAALC develop from the neuroectoderm. BAALC is located both in the membrane and in the cytoplasma, it exists as multiple alternatively spliced isoform.
ncbi acc num :
NP_001019543.1
ncbi gb acc num :
NM_001024372.1
ncbi mol weight :
5,663 Da
ncbi summary :
This gene was identified by gene expression studies in patients with acute myeloid leukemia (AML). The gene is conserved among mammals and is not found in lower organisms. Tissues that express this gene develop from the neuroectoderm. Multiple alternatively spliced transcript variants that encode different proteins have been described for this gene; however, some of the transcript variants are found only in AML cell lines. [provided by RefSeq, Jul 2008]